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- W2953287466 abstract "The catalytic modification of the Sharpless-epoxidation reaction was employed in a short EPC-synthesis of the title compound. The asymmetric epoxidation of the allylic alcohol (6) proceeded in 75 % yield and 94 % enantiomeric excess. In a 4 step sequence the epoxide (7) was transfor- med to (S)-3-hydroxy-3-mercaptomethylquinuclidine (11)" @default.
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- W2953287466 date "1994-01-01" @default.
- W2953287466 modified "2023-09-27" @default.
- W2953287466 title "EPC-Synthesis of (S)-3-Hydroxy-3-mercaptomethylquinuclidine, a Chiral Building Block for the Synthesis of the Muscarinic Agonist AF 102B" @default.
- W2953287466 doi "https://doi.org/10.3987/com-94-6758" @default.
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