Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953297488> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2953297488 endingPage "1299" @default.
- W2953297488 startingPage "1293" @default.
- W2953297488 abstract "The alkylation of o-(2-, 3- and 4-pyridyl)-3-hydroxythiophenes has been investigated. In the case of 4-(2-, 3- and 4-pyridyl)-3-hydroxythiophene systems, the soft alkylating reagent, methyl iodide, using sodium hydride as the base and dimethylimidazolidinone as the solvent, gave rise to a mixture of O-alkylated and O,C-dialkylated products in the proportions of 4.6–6.5 to 1. However, in the case of 2-(2-, 3- and 4-pyridyl)-3-hydroxythiophene systems, the same reaction conditions brought about exclusively O-alkylated compounds in yields of 45–53%. In both cases, the hard alkylating reagent, methyl p-toluenesulfonate, with the same base and solvent, only give O-alkylated compounds in yields of 51–77%. These latter conditions resulted in a good preparative route for the regiospecific formation of o-pyridyl-3-alkoxythiophenes by using ethyl 2-bromopro-pionate as well as methyl p-toluenesulfonate as alkylating reagents. The hydrolysis of the esters, derived from alkylation with ethyl 2-bromopropionate, has also been investigated." @default.
- W2953297488 created "2019-06-27" @default.
- W2953297488 creator A5008614366 @default.
- W2953297488 creator A5064686110 @default.
- W2953297488 creator A5068625548 @default.
- W2953297488 date "1993-10-01" @default.
- W2953297488 modified "2023-10-18" @default.
- W2953297488 title "Pyridine-substituted hydroxythiophenes.II. Alkylation ofo-(2-, 3- and 4-pyridyl)-3-hydroxythiophenes: Regiospecific formation ofo-pyridyl-3-alkoxythiophenes" @default.
- W2953297488 cites W1536189295 @default.
- W2953297488 cites W1991903633 @default.
- W2953297488 cites W1997444423 @default.
- W2953297488 cites W2007895544 @default.
- W2953297488 cites W2010517755 @default.
- W2953297488 cites W2034007656 @default.
- W2953297488 cites W2040406200 @default.
- W2953297488 cites W2070419964 @default.
- W2953297488 cites W2071382902 @default.
- W2953297488 cites W2949995883 @default.
- W2953297488 doi "https://doi.org/10.1002/jhet.5570300520" @default.
- W2953297488 hasPublicationYear "1993" @default.
- W2953297488 type Work @default.
- W2953297488 sameAs 2953297488 @default.
- W2953297488 citedByCount "4" @default.
- W2953297488 crossrefType "journal-article" @default.
- W2953297488 hasAuthorship W2953297488A5008614366 @default.
- W2953297488 hasAuthorship W2953297488A5064686110 @default.
- W2953297488 hasAuthorship W2953297488A5068625548 @default.
- W2953297488 hasConcept C134306372 @default.
- W2953297488 hasConcept C155647269 @default.
- W2953297488 hasConcept C161790260 @default.
- W2953297488 hasConcept C164361826 @default.
- W2953297488 hasConcept C178790620 @default.
- W2953297488 hasConcept C185592680 @default.
- W2953297488 hasConcept C2776643749 @default.
- W2953297488 hasConcept C2778870691 @default.
- W2953297488 hasConcept C2779485729 @default.
- W2953297488 hasConcept C2780059344 @default.
- W2953297488 hasConcept C2780073701 @default.
- W2953297488 hasConcept C2780471494 @default.
- W2953297488 hasConcept C33923547 @default.
- W2953297488 hasConcept C40875361 @default.
- W2953297488 hasConcept C42058472 @default.
- W2953297488 hasConcept C94412978 @default.
- W2953297488 hasConceptScore W2953297488C134306372 @default.
- W2953297488 hasConceptScore W2953297488C155647269 @default.
- W2953297488 hasConceptScore W2953297488C161790260 @default.
- W2953297488 hasConceptScore W2953297488C164361826 @default.
- W2953297488 hasConceptScore W2953297488C178790620 @default.
- W2953297488 hasConceptScore W2953297488C185592680 @default.
- W2953297488 hasConceptScore W2953297488C2776643749 @default.
- W2953297488 hasConceptScore W2953297488C2778870691 @default.
- W2953297488 hasConceptScore W2953297488C2779485729 @default.
- W2953297488 hasConceptScore W2953297488C2780059344 @default.
- W2953297488 hasConceptScore W2953297488C2780073701 @default.
- W2953297488 hasConceptScore W2953297488C2780471494 @default.
- W2953297488 hasConceptScore W2953297488C33923547 @default.
- W2953297488 hasConceptScore W2953297488C40875361 @default.
- W2953297488 hasConceptScore W2953297488C42058472 @default.
- W2953297488 hasConceptScore W2953297488C94412978 @default.
- W2953297488 hasIssue "5" @default.
- W2953297488 hasLocation W29532974881 @default.
- W2953297488 hasOpenAccess W2953297488 @default.
- W2953297488 hasPrimaryLocation W29532974881 @default.
- W2953297488 hasRelatedWork W2040058370 @default.
- W2953297488 hasRelatedWork W2051014678 @default.
- W2953297488 hasRelatedWork W2069247895 @default.
- W2953297488 hasRelatedWork W2081971561 @default.
- W2953297488 hasRelatedWork W2105136445 @default.
- W2953297488 hasRelatedWork W2949950334 @default.
- W2953297488 hasRelatedWork W2952273643 @default.
- W2953297488 hasRelatedWork W2952298580 @default.
- W2953297488 hasRelatedWork W2953297488 @default.
- W2953297488 hasRelatedWork W3015907157 @default.
- W2953297488 hasVolume "30" @default.
- W2953297488 isParatext "false" @default.
- W2953297488 isRetracted "false" @default.
- W2953297488 magId "2953297488" @default.
- W2953297488 workType "article" @default.