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- W2953353952 abstract "The N7−C25 fragment of the potent and selective cytotoxic agent psymberin has been prepared through a short (12 linear steps, 15 total steps) and stereoselective sequence. Highlights of this route include a very rapid construction of the pentasubstituted arene, a substrate-controlled diastereoselective fragment coupling using a Mukaiyama aldol reaction, and an efficient entry into a key tetrahydropyranyl cyanide." @default.
- W2953353952 created "2019-06-27" @default.
- W2953353952 creator A5058509481 @default.
- W2953353952 creator A5072483856 @default.
- W2953353952 date "2005-10-08" @default.
- W2953353952 modified "2023-10-10" @default.
- W2953353952 title "Concise and Stereoselective Synthesis of the N<sub>7</sub>−C<sub>25</sub> Fragment of Psymberin" @default.
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- W2953353952 doi "https://doi.org/10.1021/ol0520267" @default.
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