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- W2953441449 abstract "Peritoneal fibrosis is a major cause of ultrafiltration failure in continuous ambulatory peritoneal dialysis (CAPD) patients. 5-hydroxytryptamine (5-HT; Serotonin) strongly induces extracellular matrix synthesis in peritoneal fibroblasts in a Transforming growth factor beta 1 (TGF-β1) dependent manner. We aimed to evaluate anti-fibrotic role of inhibitors of 5-HT2 and 5-HT2B (Terguride and SB204741), respectively in human peritoneal fibroblasts (HPFB) isolated from peritoneum of CAPD patients." @default.
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- W2953441449 date "2019-07-01" @default.
- W2953441449 modified "2023-09-27" @default.
- W2953441449 title "SUN-146 5-HT2 AND 5-HT2B RECEPTOR INHIBITION ATTENUATE PERITONEAL FIBROSIS BY TARGETING NON-CANONICAL SIGNALING PATHWAYS INCLUDING STAT3" @default.
- W2953441449 doi "https://doi.org/10.1016/j.ekir.2019.05.547" @default.
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