FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953586216> ?p ?o ?g. }

• W2953586216 abstract "Abstract In this paper, we report studies concerning thrombin binding aptamer (TBA) dimeric derivatives in which the 3′-ends of two TBA sequences have been joined by means of linkers containing adenosine or thymidine residues and/or a glycerol moiety. CD and electrophoretic investigations indicate that all modified aptamers are able to form G-quadruplex domains resembling that of the parent TBA structure. However, isothermal titration calorimetry measurements of the aptamer/thrombin interaction point to different affinities to the target protein, depending on the type of linker. Consistently, the best ligands for thrombin show anticoagulant activities higher than TBA. Interestingly, two dimeric aptamers with the most promising properties also show far higher resistances in biological environment than TBA." @default.
• W2953586216 created "2019-07-12" @default.
• W2953586216 creator A5007342977 @default.
• W2953586216 creator A5031631274 @default.
• W2953586216 creator A5065772439 @default.
• W2953586216 creator A5066988395 @default.
• W2953586216 creator A5072870498 @default.
• W2953586216 creator A5079548793 @default.
• W2953586216 creator A5081575378 @default.
• W2953586216 creator A5090879878 @default.
• W2953586216 date "2019-06-24" @default.
• W2953586216 modified "2023-09-28" @default.
• W2953586216 title "Investigating the properties of TBA variants with twin thrombin binding domains" @default.
• W2953586216 cites W1908975171 @default.
• W2953586216 cites W1964890218 @default.
• W2953586216 cites W1968125032 @default.
• W2953586216 cites W2008978445 @default.
• W2953586216 cites W2035509237 @default.
• W2953586216 cites W2042256239 @default.
• W2953586216 cites W2127353937 @default.
• W2953586216 cites W2131465802 @default.
• W2953586216 cites W2137132263 @default.
• W2953586216 cites W2147264095 @default.
• W2953586216 cites W2150269606 @default.
• W2953586216 cites W2150663919 @default.
• W2953586216 cites W2164730913 @default.
• W2953586216 cites W2170217352 @default.
• W2953586216 cites W2175910129 @default.
• W2953586216 cites W2325630269 @default.
• W2953586216 cites W2341052016 @default.
• W2953586216 cites W2486944966 @default.
• W2953586216 cites W2521066371 @default.
• W2953586216 cites W2623004243 @default.
• W2953586216 cites W2772134404 @default.
• W2953586216 cites W2886200151 @default.
• W2953586216 cites W2917067476 @default.
• W2953586216 doi "https://doi.org/10.1038/s41598-019-45526-z" @default.
• W2953586216 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6591170" @default.
• W2953586216 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31235717" @default.
• W2953586216 hasPublicationYear "2019" @default.
• W2953586216 type Work @default.
• W2953586216 sameAs 2953586216 @default.
• W2953586216 citedByCount "17" @default.
• W2953586216 countsByYear W29535862162019 @default.
• W2953586216 countsByYear W29535862162020 @default.
• W2953586216 countsByYear W29535862162021 @default.
• W2953586216 countsByYear W29535862162022 @default.
• W2953586216 crossrefType "journal-article" @default.
• W2953586216 hasAuthorship W2953586216A5007342977 @default.
• W2953586216 hasAuthorship W2953586216A5031631274 @default.
• W2953586216 hasAuthorship W2953586216A5065772439 @default.
• W2953586216 hasAuthorship W2953586216A5066988395 @default.
• W2953586216 hasAuthorship W2953586216A5072870498 @default.
• W2953586216 hasAuthorship W2953586216A5079548793 @default.
• W2953586216 hasAuthorship W2953586216A5081575378 @default.
• W2953586216 hasAuthorship W2953586216A5090879878 @default.
• W2953586216 hasBestOaLocation W29535862161 @default.
• W2953586216 hasConcept C111919701 @default.
• W2953586216 hasConcept C12554922 @default.
• W2953586216 hasConcept C128972844 @default.
• W2953586216 hasConcept C153911025 @default.
• W2953586216 hasConcept C156911925 @default.
• W2953586216 hasConcept C185592680 @default.
• W2953586216 hasConcept C203014093 @default.
• W2953586216 hasConcept C21951064 @default.
• W2953586216 hasConcept C2776568683 @default.
• W2953586216 hasConcept C2777292125 @default.
• W2953586216 hasConcept C2778271848 @default.
• W2953586216 hasConcept C2780557392 @default.
• W2953586216 hasConcept C41008148 @default.
• W2953586216 hasConcept C55493867 @default.
• W2953586216 hasConcept C71240020 @default.
• W2953586216 hasConcept C86803240 @default.
• W2953586216 hasConcept C89560881 @default.
• W2953586216 hasConceptScore W2953586216C111919701 @default.
• W2953586216 hasConceptScore W2953586216C12554922 @default.
• W2953586216 hasConceptScore W2953586216C128972844 @default.
• W2953586216 hasConceptScore W2953586216C153911025 @default.
• W2953586216 hasConceptScore W2953586216C156911925 @default.
• W2953586216 hasConceptScore W2953586216C185592680 @default.
• W2953586216 hasConceptScore W2953586216C203014093 @default.
• W2953586216 hasConceptScore W2953586216C21951064 @default.
• W2953586216 hasConceptScore W2953586216C2776568683 @default.
• W2953586216 hasConceptScore W2953586216C2777292125 @default.
• W2953586216 hasConceptScore W2953586216C2778271848 @default.
• W2953586216 hasConceptScore W2953586216C2780557392 @default.
• W2953586216 hasConceptScore W2953586216C41008148 @default.
• W2953586216 hasConceptScore W2953586216C55493867 @default.
• W2953586216 hasConceptScore W2953586216C71240020 @default.
• W2953586216 hasConceptScore W2953586216C86803240 @default.
• W2953586216 hasConceptScore W2953586216C89560881 @default.
• W2953586216 hasIssue "1" @default.
• W2953586216 hasLocation W29535862161 @default.
• W2953586216 hasLocation W29535862162 @default.
• W2953586216 hasLocation W29535862163 @default.
• W2953586216 hasOpenAccess W2953586216 @default.
• W2953586216 hasPrimaryLocation W29535862161 @default.
• W2953586216 hasRelatedWork W2005412761 @default.
• W2953586216 hasRelatedWork W2022022212 @default.
• W2953586216 hasRelatedWork W2033523361 @default.

• next