FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953617761> ?p ?o ?g. }

• W2953617761 endingPage "2240.e15" @default.
• W2953617761 startingPage "2230" @default.
• W2953617761 abstract "ObjectiveThe Cardiothoracic Surgical Trials Network reported that left ventricular reverse remodeling at 2 years did not differ between patients with moderate ischemic mitral regurgitation randomized to coronary artery bypass grafting plus mitral valve repair (n = 150) or coronary artery bypass grafting alone (n = 151). To address health resource use implications, we compared costs and quality-adjusted survival.MethodsWe used individual patient data from the Cardiothoracic Surgical Trials Network trial on survival, hospitalizations, quality of life, and US hospitalization costs to estimate cumulative costs and quality-adjusted life years. A microsimulation model was developed to extrapolate to 10 years. Bootstrap and deterministic sensitivity analyses were performed to address uncertainty.ResultsIn-hospital costs were $59,745 for coronary artery bypass grafting plus mitral valve repair versus $51,326 for coronary artery bypass grafting alone (difference $8419; 95% uncertainty interval, 2259-18,757). Two-year costs were $81,263 versus $67,341 (difference 13,922 [2370 to 28,888]), and quality-adjusted life years were 1.35 versus 1.30 (difference 0.05; −0.04 to 0.14), resulting in an incremental cost-effectiveness ratio of $308,343/quality-adjusted life year for coronary artery bypass grafting plus mitral valve repair. At 10 years, its costs remained higher ($107,733 vs $88,583, difference 19,150 [−3866 to 56,826]) and quality-adjusted life years showed no difference (−0.92 to 0.87), with 5.08 versus 5.08. The likelihood that coronary artery bypass grafting plus mitral valve repair would be considered cost-effective at 10 years based on a cost-effectiveness threshold of $100K/quality-adjusted life year did not exceed 37%. Only when this procedure reduces the death rate by a relative 5% will the incremental cost-effectiveness ratio fall below $100K/quality-adjusted life year.Conclusions:The addition of mitral valve repair to coronary artery bypass grafting for patients with moderate ischemic mitral regurgitation is unlikely to be cost-effective. Only if late mortality benefits can be demonstrated will it meet commonly used cost-effectiveness criteria." @default.
• W2953617761 created "2019-07-12" @default.
• W2953617761 creator A5001278852 @default.
• W2953617761 creator A5001335430 @default.
• W2953617761 creator A5001913523 @default.
• W2953617761 creator A5001986733 @default.
• W2953617761 creator A5002117710 @default.
• W2953617761 creator A5002350476 @default.
• W2953617761 creator A5002987310 @default.
• W2953617761 creator A5003737429 @default.
• W2953617761 creator A5003899849 @default.
• W2953617761 creator A5004224848 @default.
• W2953617761 creator A5004913924 @default.
• W2953617761 creator A5004932640 @default.
• W2953617761 creator A5004980235 @default.
• W2953617761 creator A5005949077 @default.
• W2953617761 creator A5005974698 @default.
• W2953617761 creator A5006638778 @default.
• W2953617761 creator A5007010729 @default.
• W2953617761 creator A5007048499 @default.
• W2953617761 creator A5007100682 @default.
• W2953617761 creator A5007473059 @default.
• W2953617761 creator A5007508560 @default.
• W2953617761 creator A5007678309 @default.
• W2953617761 creator A5008331271 @default.
• W2953617761 creator A5009748989 @default.
• W2953617761 creator A5009912525 @default.
• W2953617761 creator A5010411278 @default.
• W2953617761 creator A5010742481 @default.
• W2953617761 creator A5010835143 @default.
• W2953617761 creator A5011023346 @default.
• W2953617761 creator A5011661315 @default.
• W2953617761 creator A5012657061 @default.
• W2953617761 creator A5013241838 @default.
• W2953617761 creator A5013305897 @default.
• W2953617761 creator A5013528021 @default.
• W2953617761 creator A5013815548 @default.
• W2953617761 creator A5015007505 @default.
• W2953617761 creator A5015021993 @default.
• W2953617761 creator A5015157946 @default.
• W2953617761 creator A5015948386 @default.
• W2953617761 creator A5016806686 @default.
• W2953617761 creator A5017176898 @default.
• W2953617761 creator A5017557916 @default.
• W2953617761 creator A5018417740 @default.
• W2953617761 creator A5018667119 @default.
• W2953617761 creator A5019000570 @default.
• W2953617761 creator A5019059801 @default.
• W2953617761 creator A5019062163 @default.
• W2953617761 creator A5019832398 @default.
• W2953617761 creator A5019956063 @default.
• W2953617761 creator A5020593962 @default.
• W2953617761 creator A5020637999 @default.
• W2953617761 creator A5021474585 @default.
• W2953617761 creator A5022236104 @default.
• W2953617761 creator A5022578470 @default.
• W2953617761 creator A5022745714 @default.
• W2953617761 creator A5023118684 @default.
• W2953617761 creator A5023860683 @default.
• W2953617761 creator A5024324970 @default.
• W2953617761 creator A5024930363 @default.
• W2953617761 creator A5025152450 @default.
• W2953617761 creator A5025927005 @default.
• W2953617761 creator A5026093431 @default.
• W2953617761 creator A5026164959 @default.
• W2953617761 creator A5026351730 @default.
• W2953617761 creator A5026371597 @default.
• W2953617761 creator A5026552162 @default.
• W2953617761 creator A5026740203 @default.
• W2953617761 creator A5026972134 @default.
• W2953617761 creator A5027419207 @default.
• W2953617761 creator A5028412398 @default.
• W2953617761 creator A5028502269 @default.
• W2953617761 creator A5028785465 @default.
• W2953617761 creator A5028788015 @default.
• W2953617761 creator A5029542482 @default.
• W2953617761 creator A5030148643 @default.
• W2953617761 creator A5030183182 @default.
• W2953617761 creator A5030304785 @default.
• W2953617761 creator A5030428751 @default.
• W2953617761 creator A5030617028 @default.
• W2953617761 creator A5031326871 @default.
• W2953617761 creator A5032451536 @default.
• W2953617761 creator A5032957753 @default.
• W2953617761 creator A5033090327 @default.
• W2953617761 creator A5033993082 @default.
• W2953617761 creator A5034367622 @default.
• W2953617761 creator A5034586607 @default.
• W2953617761 creator A5034766126 @default.
• W2953617761 creator A5035043566 @default.
• W2953617761 creator A5035463266 @default.
• W2953617761 creator A5035541862 @default.
• W2953617761 creator A5035612714 @default.
• W2953617761 creator A5036029994 @default.
• W2953617761 creator A5036223986 @default.
• W2953617761 creator A5037277344 @default.
• W2953617761 creator A5038492119 @default.
• W2953617761 creator A5038696405 @default.

• next