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• W2953638337 abstract "PURPOSE: The purpose of this study was to examine how menopausal status affects choice reaction time and peripheral BDNF levels after aerobic exercise. It was hypothesized that exercise would affect peripheral BDNF levels and choice reaction time similarly among pre and postmenopausal women. METHODS: The subjects consisted of 14 active females (7 premenopausal and 7 postmenopausal). Subjects went through two different trials: an exercise trial and a controlled reading trials. The exercise trial consisted of running on a treadmill at 75% of VO2max for 30 minutes. The control trial consisted of a reading session. A computerized Stroop test was given to assess choice reaction time, and blood samples were obtained before, immediately after, and 30 minutes after the exercise and control trials. RESULTS: Exercise did not lead to a significant change in BDNF in either group. However, there was a statistical interaction (P=0.041) between pre and postmenopausal women over time between pre and post timepoints, with premenopausal women trending towards an increase in BDNF, and postmenopausal women trending towards a decrease in BDNF. There was a large effect size within this interaction represented with a partial eta squared value of .265. A Post Hoc test was done to further investigate the interaction. There was not enough statistical power (P = .164) to state that there was a difference in BDNF levels (pre to post) but that there appears to be a trend. Both age and FSH had indirect relationships with BDNF (p<0.05); the greater the age or FSH, the lower the peripheral BDNF levels. There was a positive correlation between age and Stroop Test time over all time points (P = .039, .089, and .027; pre, post, and post30 exercise respectively). This indicated an age-related decline in choice reaction time capabilities. CONCLUSION: Within the study, there was not statistical evidence that acute exercise affects BDNF levels nor choice reaction time for the Stroop incongruent test, regardless of menopausal status. However, a clear decline in choice reaction time was noted with increase age. Additionally, there appears to be a blunting of exercise-induced increases in BDNF in postmenopausal women. Further investigation is required to clarify this relationship." @default.
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• W2953638337 date "2019-06-01" @default.
• W2953638337 modified "2023-09-27" @default.
• W2953638337 title "The Effects Of Acute Aerobic Exercise On BDNF Levels And Cognition In Postmenopausal Women" @default.
• W2953638337 doi "https://doi.org/10.1249/01.mss.0000562161.71215.f1" @default.
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