Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953647828> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2953647828 endingPage "779" @default.
- W2953647828 startingPage "774" @default.
- W2953647828 abstract "Abstract Purpose To describe the first 13 years of anti‐vascular endothelial growth factor (anti‐ VEGF ) therapy from the perspective of a public ophthalmic department serving a local community of almost one million people. Methods Retrospective registry study. Data from Oslo University Hospital, Norway were collected from 2006 through 2018. Hospital episode statistics were searched for episodes of care encompassing intravitreal anti‐ VEGF procedures. Patient‐specific ID numbers, diagnoses, and drug codes were registered. In general, bevacizumab was used as first‐line treatment, with aflibercept reserved for resistant cases from 2013. Results The number of unique patients treated per year increased from 130 in 2006 to 3428 in 2018. In 2018, 2488 (73%) patients had also received treatment the previous year. The number of yearly injections increased from 228 in 2006 to 25 570 in 2018. In 2018 the diagnosis macular degeneration constituted 69% of injections, diabetic retinopathy constituted 15%, retinal vein occlusion constituted 13%, and other diagnoses constituted 3%. In the same year 49% of injections were with bevacizumab, 46% with aflibercept, 4% with ranibizumab, and 1% with dexamethasone implants. The bevacizumab to aflibercept ratio was almost 1:1 for macular degeneration and diabetic retinopathy; for retinal vein occlusion the ratio was 13:7. Conclusion In 13 years there was an approximately 100‐fold increase in the number of yearly intravitreal injections. A majority of patients received long‐term treatment. Macular degeneration was the most common diagnosis. Using bevacizumab as first‐line treatment, with aflibercept reserved for resistant cases from 2013, eventually resulted in a nearly 1:1 ratio in drug usage." @default.
- W2953647828 created "2019-07-12" @default.
- W2953647828 creator A5004263190 @default.
- W2953647828 creator A5023800104 @default.
- W2953647828 creator A5027804976 @default.
- W2953647828 creator A5064601650 @default.
- W2953647828 creator A5076708868 @default.
- W2953647828 date "2019-07-01" @default.
- W2953647828 modified "2023-10-17" @default.
- W2953647828 title "Thirteen years of intravitreal anti‐vascular endothelial growth factor therapy: the promises and burdens of a paradigm shift told from the perspective of the largest retina service in Norway." @default.
- W2953647828 cites W1500728559 @default.
- W2953647828 cites W1695648665 @default.
- W2953647828 cites W1782061354 @default.
- W2953647828 cites W1786299986 @default.
- W2953647828 cites W1969840258 @default.
- W2953647828 cites W2004117352 @default.
- W2953647828 cites W2042978638 @default.
- W2953647828 cites W2152816807 @default.
- W2953647828 cites W2171962482 @default.
- W2953647828 cites W2618105561 @default.
- W2953647828 cites W2754502683 @default.
- W2953647828 cites W2805449877 @default.
- W2953647828 cites W2805652106 @default.
- W2953647828 doi "https://doi.org/10.1111/aos.14177" @default.
- W2953647828 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31264363" @default.
- W2953647828 hasPublicationYear "2019" @default.
- W2953647828 type Work @default.
- W2953647828 sameAs 2953647828 @default.
- W2953647828 citedByCount "9" @default.
- W2953647828 countsByYear W29536478282021 @default.
- W2953647828 countsByYear W29536478282022 @default.
- W2953647828 countsByYear W29536478282023 @default.
- W2953647828 crossrefType "journal-article" @default.
- W2953647828 hasAuthorship W2953647828A5004263190 @default.
- W2953647828 hasAuthorship W2953647828A5023800104 @default.
- W2953647828 hasAuthorship W2953647828A5027804976 @default.
- W2953647828 hasAuthorship W2953647828A5064601650 @default.
- W2953647828 hasAuthorship W2953647828A5076708868 @default.
- W2953647828 hasBestOaLocation W29536478281 @default.
- W2953647828 hasConcept C118487528 @default.
- W2953647828 hasConcept C134018914 @default.
- W2953647828 hasConcept C141071460 @default.
- W2953647828 hasConcept C167135981 @default.
- W2953647828 hasConcept C2776403814 @default.
- W2953647828 hasConcept C2776694085 @default.
- W2953647828 hasConcept C2777802072 @default.
- W2953647828 hasConcept C2778749236 @default.
- W2953647828 hasConcept C2779829184 @default.
- W2953647828 hasConcept C2780699112 @default.
- W2953647828 hasConcept C2781100027 @default.
- W2953647828 hasConcept C555293320 @default.
- W2953647828 hasConcept C71924100 @default.
- W2953647828 hasConceptScore W2953647828C118487528 @default.
- W2953647828 hasConceptScore W2953647828C134018914 @default.
- W2953647828 hasConceptScore W2953647828C141071460 @default.
- W2953647828 hasConceptScore W2953647828C167135981 @default.
- W2953647828 hasConceptScore W2953647828C2776403814 @default.
- W2953647828 hasConceptScore W2953647828C2776694085 @default.
- W2953647828 hasConceptScore W2953647828C2777802072 @default.
- W2953647828 hasConceptScore W2953647828C2778749236 @default.
- W2953647828 hasConceptScore W2953647828C2779829184 @default.
- W2953647828 hasConceptScore W2953647828C2780699112 @default.
- W2953647828 hasConceptScore W2953647828C2781100027 @default.
- W2953647828 hasConceptScore W2953647828C555293320 @default.
- W2953647828 hasConceptScore W2953647828C71924100 @default.
- W2953647828 hasIssue "8" @default.
- W2953647828 hasLocation W29536478281 @default.
- W2953647828 hasLocation W29536478282 @default.
- W2953647828 hasOpenAccess W2953647828 @default.
- W2953647828 hasPrimaryLocation W29536478281 @default.
- W2953647828 hasRelatedWork W2034093159 @default.
- W2953647828 hasRelatedWork W2049577742 @default.
- W2953647828 hasRelatedWork W2123096760 @default.
- W2953647828 hasRelatedWork W2336111296 @default.
- W2953647828 hasRelatedWork W2519403553 @default.
- W2953647828 hasRelatedWork W2522975619 @default.
- W2953647828 hasRelatedWork W2553987180 @default.
- W2953647828 hasRelatedWork W2577193304 @default.
- W2953647828 hasRelatedWork W2885663288 @default.
- W2953647828 hasRelatedWork W4243304339 @default.
- W2953647828 hasVolume "98" @default.
- W2953647828 isParatext "false" @default.
- W2953647828 isRetracted "false" @default.
- W2953647828 magId "2953647828" @default.
- W2953647828 workType "article" @default.