FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953676289> ?p ?o ?g. }

• W2953676289 endingPage "362" @default.
• W2953676289 startingPage "356" @default.
• W2953676289 abstract "Abstract Aims/Introduction The aim of the present study was to compare the clinical and genetic characteristics between people with type 1 diabetes who were positive and negative for autoantibodies against glutamic acid decarboxylase ( GADA ) measured by enzyme‐linked immunosorbent assay ( ELISA ) with low‐titer GADA measured by radioimmunoassay. Materials and Methods Among Japanese people with type 1 diabetes in whom GADA were measured by both ELISA and radioimmunoassay, those who had low titers of GADA measured by radioimmunoassay (1.5–10 U/ mL ), regardless of positivity for GADA measured by ELISA , were studied. There were 65 participants with acute‐onset type 1 diabetes and 30 participants with slowly progressive insulin‐dependent diabetes mellitus. Clinical characteristics and human leukocyte antigen types were compared in ELISA ‐positive (≥5 U/ mL ) and ELISA ‐negative participants. Endogenous insulin secretion was evaluated by C‐peptide index. Results Among participants with slowly progressive insulin‐dependent diabetes mellitus, postprandial C‐peptide index was significantly higher in ELISA ‐negative participants than in ELISA ‐positive participants ( r = 0.619, P = 0.002). Among 52 participants whose human leukocyte antigen typing was carried out, all of the participants with slowly progressive insulin‐dependent diabetes mellitus who had DRB 1*09:01 were positive by GADA ‐ ELISA ( P = 0.021). In acute‐onset type 1 diabetes participants, there were no significant differences for the C‐peptide index and human leukocyte antigen genotypes. Conclusions The difference in the positivity for GADA ‐ ELISA might reflect cytotoxicity toward pancreatic β‐cells and preservation of endogenous insulin secretion in people with slowly progressive insulin‐dependent diabetes mellitus. We also suggest that the difference in the GADA ‐ ELISA ‐specific epitope depends on the human leukocyte antigen genotype." @default.
• W2953676289 created "2019-07-12" @default.
• W2953676289 creator A5034532366 @default.
• W2953676289 creator A5040965633 @default.
• W2953676289 creator A5059304861 @default.
• W2953676289 creator A5074615496 @default.
• W2953676289 creator A5077370623 @default.
• W2953676289 date "2019-08-01" @default.
• W2953676289 modified "2023-10-01" @default.
• W2953676289 title "Clinical and genetic characteristics of people with type 1 diabetes who have discrepancies in titers of anti‐glutamic acid decarboxylase antibody measured by radioimmunoassay and enzyme‐linked immunosorbent assay" @default.
• W2953676289 cites W1540221646 @default.
• W2953676289 cites W1601298625 @default.
• W2953676289 cites W2030875300 @default.
• W2953676289 cites W2049583719 @default.
• W2953676289 cites W2058861592 @default.
• W2953676289 cites W2070645808 @default.
• W2953676289 cites W2116230803 @default.
• W2953676289 cites W2119218381 @default.
• W2953676289 cites W2166526152 @default.
• W2953676289 cites W2167007291 @default.
• W2953676289 cites W2167296070 @default.
• W2953676289 cites W2167313288 @default.
• W2953676289 cites W2383035231 @default.
• W2953676289 cites W2533492047 @default.
• W2953676289 cites W263868151 @default.
• W2953676289 cites W2906310085 @default.
• W2953676289 cites W4233475725 @default.
• W2953676289 cites W4244323884 @default.
• W2953676289 cites W4254965081 @default.
• W2953676289 doi "https://doi.org/10.1111/jdi.13111" @default.
• W2953676289 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7078079" @default.
• W2953676289 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31267698" @default.
• W2953676289 hasPublicationYear "2019" @default.
• W2953676289 type Work @default.
• W2953676289 sameAs 2953676289 @default.
• W2953676289 citedByCount "4" @default.
• W2953676289 countsByYear W29536762892021 @default.
• W2953676289 countsByYear W29536762892022 @default.
• W2953676289 countsByYear W29536762892023 @default.
• W2953676289 crossrefType "journal-article" @default.
• W2953676289 hasAuthorship W2953676289A5034532366 @default.
• W2953676289 hasAuthorship W2953676289A5040965633 @default.
• W2953676289 hasAuthorship W2953676289A5059304861 @default.
• W2953676289 hasAuthorship W2953676289A5074615496 @default.
• W2953676289 hasAuthorship W2953676289A5077370623 @default.
• W2953676289 hasBestOaLocation W29536762891 @default.
• W2953676289 hasConcept C126322002 @default.
• W2953676289 hasConcept C134018914 @default.
• W2953676289 hasConcept C147483822 @default.
• W2953676289 hasConcept C159654299 @default.
• W2953676289 hasConcept C163764329 @default.
• W2953676289 hasConcept C176685330 @default.
• W2953676289 hasConcept C181199279 @default.
• W2953676289 hasConcept C203014093 @default.
• W2953676289 hasConcept C2778875212 @default.
• W2953676289 hasConcept C2779306644 @default.
• W2953676289 hasConcept C2781232474 @default.
• W2953676289 hasConcept C32611913 @default.
• W2953676289 hasConcept C55493867 @default.
• W2953676289 hasConcept C555293320 @default.
• W2953676289 hasConcept C71924100 @default.
• W2953676289 hasConcept C86803240 @default.
• W2953676289 hasConcept C9497952 @default.
• W2953676289 hasConceptScore W2953676289C126322002 @default.
• W2953676289 hasConceptScore W2953676289C134018914 @default.
• W2953676289 hasConceptScore W2953676289C147483822 @default.
• W2953676289 hasConceptScore W2953676289C159654299 @default.
• W2953676289 hasConceptScore W2953676289C163764329 @default.
• W2953676289 hasConceptScore W2953676289C176685330 @default.
• W2953676289 hasConceptScore W2953676289C181199279 @default.
• W2953676289 hasConceptScore W2953676289C203014093 @default.
• W2953676289 hasConceptScore W2953676289C2778875212 @default.
• W2953676289 hasConceptScore W2953676289C2779306644 @default.
• W2953676289 hasConceptScore W2953676289C2781232474 @default.
• W2953676289 hasConceptScore W2953676289C32611913 @default.
• W2953676289 hasConceptScore W2953676289C55493867 @default.
• W2953676289 hasConceptScore W2953676289C555293320 @default.
• W2953676289 hasConceptScore W2953676289C71924100 @default.
• W2953676289 hasConceptScore W2953676289C86803240 @default.
• W2953676289 hasConceptScore W2953676289C9497952 @default.
• W2953676289 hasIssue "2" @default.
• W2953676289 hasLocation W29536762891 @default.
• W2953676289 hasLocation W29536762892 @default.
• W2953676289 hasLocation W29536762893 @default.
• W2953676289 hasLocation W29536762894 @default.
• W2953676289 hasOpenAccess W2953676289 @default.
• W2953676289 hasPrimaryLocation W29536762891 @default.
• W2953676289 hasRelatedWork W138803513 @default.
• W2953676289 hasRelatedWork W2000308085 @default.
• W2953676289 hasRelatedWork W2029210465 @default.
• W2953676289 hasRelatedWork W2045823137 @default.
• W2953676289 hasRelatedWork W2048226041 @default.
• W2953676289 hasRelatedWork W2072014172 @default.
• W2953676289 hasRelatedWork W2077311996 @default.
• W2953676289 hasRelatedWork W2086423568 @default.
• W2953676289 hasRelatedWork W2127439265 @default.
• W2953676289 hasRelatedWork W2418646588 @default.
• W2953676289 hasVolume "11" @default.

• next