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- W2953804711 abstract "Introduction: Thrombotic Thrombocytopenic Purpura (TTP) is a fulminant thromboticmicroangiopathy often manifested as clinical pentad of fever, thrombocytopenia, haemolytic anemia, renal failure and neurological abnormalities. ADAMTS13 deficiency has been noted as causative factor however secondary TTP/HUS preceded by various insult is also noted. Insults like burn, malignancy, viral infections and sepsis has been associated with TTP/HUS. Association of TTP/HUS with hepatitis A infection is rare and not reported.
 Case Summary: 27 years old male was admitted with acute onset fever, drowsiness, decreased urine output and icterus. Physical examination was unremarkable except icterus. He was found to have IgM positive for hepatitis A along with evidence of microangiopathic haemolytic anemia. He was diagnosed to have Hepatitis A along with TTP/HUS and plasmapheresis was started. He improved dramatically after it. No recurrence of TTP/HUS was noted on follow up.
 Conclusion: We present an interesting case of Hepatitis A as a possible trigger for Thrombotic thrombocytopenic purpura. Any haemolytic microangiopathy in hepatitis A should be carefully looked for a possibility of TTP.
 Keywords: Thrombotic thrombocytopenic purpura, Hepatitis A, TTP/HUS, HAV" @default.
- W2953804711 created "2019-07-12" @default.
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- W2953804711 date "2019-06-25" @default.
- W2953804711 modified "2023-10-06" @default.
- W2953804711 title "AN UNUSUAL PRESENTATION OF THROMBOTIC THROMBOCYTOPENIC PURPURA FOLLOWING HEPATITIS A INFECTION: A CASE REPORT" @default.
- W2953804711 doi "https://doi.org/10.32553/ijmbs.v3i6.340" @default.
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