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- W2953832336 abstract "To assess pulmonary arteriovenous malformation (PAVM) growth among patients with untreated PAVMs using imaging from long-term follow-up per hereditary hemorrhagic telangiectasia international guidelines.Analysis included 88 untreated PAVMs from 21 patients (6 male;15 female; mean age at presentation 47 y; range, 12-68 y). Two CT studies with the longest interval between were evaluated (mean 8.4 y; median 8.8 y; range, 3.1-14.1 y). Measurement of feeding artery diameter and anteroposterior (AP) and mediolateral (ML) sac dimensions for each PAVM was performed separately by 2 radiologists blinded to patient and CT order. Statistical analysis was performed to determine change in size between earliest and follow-up imaging.Mean feeding artery diameter, AP sac dimension, and ML sac dimension were 1.4 mm (range, 0.8-3.7 mm), 4.3 mm (range, 2.1-11.1 mm), and 4.1 mm (range, 1.8-9.2 mm) on earliest imaging and 1.4 mm (range, 0.9-2.6 mm), 4.5 mm (range, 2.2-12.2 mm), and 4.3 mm (range, 2.0-9.6 mm) on follow-up. Model-based mean analysis showed no statistically significant change in dimension of any variable between earliest and follow-up imaging. Secondary analysis including age also found no statistically significant difference (feeding diameter, P = .09; AP sac dimension, P = .9; ML sac dimension, P = .1). Analysis including time between measurements found no significant relationship between change in variables and time (feeding artery diameter, P = .4; AP sac dimension, P = .3; ML sac dimension, P = .06).Untreated PAVMs grew slowly, if at all, in a near-decade span, and any demonstrated growth was minimal. These findings challenge the current recommendation of 3- to 5-year CT follow-up." @default.
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- W2953832336 date "2019-08-01" @default.
- W2953832336 modified "2023-10-01" @default.
- W2953832336 title "Lack of Growth of Small (≤2 mm Feeding Artery) Untreated Pulmonary Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia" @default.
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- W2953832336 doi "https://doi.org/10.1016/j.jvir.2019.04.009" @default.
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