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• W2953891200 abstract "Non-vitamin K antagonist (VKA) oral anticoagulants (NOACs) have several advantages over VKAs that render them an attractive option for adults with congenital heart disease (CHD). Efficacy and safety data specific to the adult CHD population are emerging. Herein, we synthesize the growing literature regarding NOACs in adults with CHD and attempt to identify subgroups for which it appears reasonable to extrapolate data from populations without CHD. Small observational studies suggest that NOACs are safe and effective in selected adults with CHD. NOACs are contraindicated in patients with a mechanical valve, in those with mitral or tricuspid valve stenosis with enlarged and diseased atria, with or without a mitral or tricuspid bioprosthesis, and after recent cardiac surgery (< 3 months). There is currently insufficient evidence to recommend NOACs in patients with a Fontan circulation or cyanotic CHD. Growing literature supports the use of NOACs in patients without CHD who have various forms of valvular heart disease. Therefore, when an indication for oral anticoagulation is established, it appears reasonable to consider a NOAC instead of a VKA in adults with CHD lesions analogous to isolated mitral regurgitation, tricuspid regurgitation, or aortic regurgitation or stenosis. The NOAC agent selected and the prescribed dose should be tailored according to bleeding risk, body weight, renal function, and comedications, especially antiepileptic drugs. The decision to initiate a NOAC should be shared between the patient and care provider. Large-scale research studies are required to further assess safety and efficacy in selected patient subgroups." @default.
• W2953891200 created "2019-07-12" @default.
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• W2953891200 date "2019-12-01" @default.
• W2953891200 modified "2023-10-03" @default.
• W2953891200 title "Non-Vitamin K Antagonist Oral Anticoagulants in Adult Congenital Heart Disease" @default.
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• W2953891200 cites W1965322531 @default.
• W2953891200 cites W1968733770 @default.
• W2953891200 cites W1971861730 @default.
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• W2953891200 doi "https://doi.org/10.1016/j.cjca.2019.06.022" @default.
• W2953891200 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31635950" @default.
• W2953891200 hasPublicationYear "2019" @default.
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