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- W2954186275 abstract "POSEIDON groups 1 and 2 patients respond poorly (<4 oocytes retrieved) or sub-optimally (4-9 oocytes retrieved) to gonadotropin stimulation despite the presence of adequate ovarian parameters, which negatively affect their cumulative chances of delivering a baby using Assisted Reproductive Technology. A polygenic trait involving gonadotropins and/or their receptors seems to be the primary pathophysiology mechanism explaining this phenomenon. The clinical management is mainly focused on maximizing oocyte yield as to increase the likelihood of having at least one euploid embryo for transfer. Indices such as FORT (follicle output rate) and FOI (follicle-to-oocyte index) may be used to determine if the ovarian reserve was properly explored during a previous ovarian stimulation. Testing for the presence of common polymorphisms affecting gonadotropins and/or their receptors can also be considered to identify patients at risk of hypo-response. An individualized estimation of the minimum number of oocytes needed to obtain at least one euploid embryo can assist counseling and treatment planning. Among currently existing pharmacological interventions, use of recombinant FSH in preference over urinary gonadotropin preparations, FSH dosage increase, and use of rLH supplementation may be considered -alone or combined- for optimally managing POSEIDON's groups 1 and 2 patients. However, given the recent introduction of the POSEIDON criteria, there is still a lack of studies examining the role of interventions specifically to patients classified as groups 1 and 2, thus making it an area for open research." @default.
- W2954186275 created "2019-07-12" @default.
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- W2954186275 date "2019-06-27" @default.
- W2954186275 modified "2023-10-10" @default.
- W2954186275 title "Management of Women With an Unexpected Low Ovarian Response to Gonadotropin" @default.
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- W2954186275 cites W1896195310 @default.
- W2954186275 cites W1924114680 @default.
- W2954186275 cites W1968729713 @default.
- W2954186275 cites W1973612506 @default.
- W2954186275 cites W1986466980 @default.
- W2954186275 cites W2018481902 @default.
- W2954186275 cites W2023369065 @default.
- W2954186275 cites W2030490673 @default.
- W2954186275 cites W2042457856 @default.
- W2954186275 cites W2044189645 @default.
- W2954186275 cites W2047284162 @default.
- W2954186275 cites W2052683724 @default.
- W2954186275 cites W2053785152 @default.
- W2954186275 cites W2055931893 @default.
- W2954186275 cites W2062608141 @default.
- W2954186275 cites W2072173486 @default.
- W2954186275 cites W2091194437 @default.
- W2954186275 cites W2093597184 @default.
- W2954186275 cites W2097339300 @default.
- W2954186275 cites W2105741157 @default.
- W2954186275 cites W2107641986 @default.
- W2954186275 cites W2109920440 @default.
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- W2954186275 cites W2123222719 @default.
- W2954186275 cites W2123606330 @default.
- W2954186275 cites W2128208951 @default.
- W2954186275 cites W2131295297 @default.
- W2954186275 cites W2131485340 @default.
- W2954186275 cites W2133496625 @default.
- W2954186275 cites W2133583710 @default.
- W2954186275 cites W2137784415 @default.
- W2954186275 cites W2138346371 @default.
- W2954186275 cites W2138564327 @default.
- W2954186275 cites W2138674040 @default.
- W2954186275 cites W2139591553 @default.
- W2954186275 cites W2140474382 @default.
- W2954186275 cites W2143320979 @default.
- W2954186275 cites W2143422132 @default.
- W2954186275 cites W2154078869 @default.
- W2954186275 cites W2154685763 @default.
- W2954186275 cites W2157586615 @default.
- W2954186275 cites W2159590033 @default.
- W2954186275 cites W2167258515 @default.
- W2954186275 cites W2272619127 @default.
- W2954186275 cites W2287263109 @default.
- W2954186275 cites W2287315831 @default.
- W2954186275 cites W2302668502 @default.
- W2954186275 cites W2309188263 @default.
- W2954186275 cites W2341575587 @default.
- W2954186275 cites W2420588108 @default.
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- W2954186275 cites W2571373723 @default.
- W2954186275 cites W2766026824 @default.
- W2954186275 cites W2771688165 @default.
- W2954186275 cites W2794881395 @default.
- W2954186275 cites W2797882356 @default.
- W2954186275 cites W2799421206 @default.
- W2954186275 cites W2806373568 @default.
- W2954186275 cites W2809154410 @default.
- W2954186275 cites W2809458474 @default.
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- W2954186275 cites W2897002518 @default.
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- W2954186275 doi "https://doi.org/10.3389/fendo.2019.00387" @default.
- W2954186275 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6610322" @default.
- W2954186275 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31316461" @default.
- W2954186275 hasPublicationYear "2019" @default.
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