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• W2954206670 abstract "•Conventional orthodontic-surgical treatment for dentofacial deformities can improve OHRQoL. •OHRQoL decreases during presurgical orthodontic treatment, particularly esthetics and function. •OHRQoL increases during postsurgical orthodontic treatment, surpassing the earlier decrease. Introduction Although conventional combined orthodontic-surgical treatment is frequently applied in orthodontic clinic practice, its actual effect on oral health–related quality of life (OHRQoL) remains inconclusive. We aimed to appraise trials investigating the effect of conventional combined orthodontic-surgical treatment on OHRQoL in patients with dentofacial deformities. Methods Electronic searches of 6 databases and manual searches were conducted up to January 2019. Randomized controlled trials, controlled clinical trials, and prospective cohort studies that investigated the impact of combined orthodontic-surgical treatment on OHRQoL using validated instruments were included. The risk of bias within individual studies was assessed with the use of the Cochrane tool or the Newcastle-Ottawa Scale according to study designs. Meta-analysis was conducted, and OHRQoL at different time points during conventional combined orthodontic-surgical treatment were statistically pooled and compared. Results Of the 893 records initially identified, 24 studies were included in this review. Relative to pretreatment, the condition-specific OHRQoL was significantly improved 6 months after surgery, particularly in the perceptions to social aspects (mean difference [MD] 4.88, 95% confidence interval [CI] 2.45 to 7.32), facial appearance (MD 5.48, 95% CI 4.18 to 6.79), and oral function (MD 4.49, 95% CI 3.27 to 5.72). In terms of changes during combined orthodontic-surgical treatment, the condition-specific OHRQoL worsened in the presurgical orthodontic treatment (MD −7.25, 95% CI −13.29 to −1.22) and improved postsurgically compared with pretreatment (MD 16.59, 95% CI 10.41 to 22.77). Similar patterns were observed in the general OHRQoL changes. Conclusions For patients undergoing combined orthodontic-surgical treatment, the OHRQoL seems to decrease temporarily in presurgical orthodontic treatment compared with pretreatment and to increase to a level better than it was before treatment during postsurgical orthodontic treatment. Based on the present review, combined orthodontic-surgical treatment could be an effective choice to improve OHRQoL for patients affected with severe dentofacial deformities." @default.
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• W2954206670 date "2019-07-01" @default.
• W2954206670 modified "2023-10-01" @default.
• W2954206670 title "Effect of conventional combined orthodontic-surgical treatment on oral health-related quality of life: A systematic review and meta-analysis" @default.
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• W2954206670 doi "https://doi.org/10.1016/j.ajodo.2019.03.008" @default.
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