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• W2954249255 startingPage "49" @default.
• W2954249255 abstract "Plant viruses are among the important pathogens that cause severe crop losses. The most efficient method to control viral diseases is currently to use virus resistant crops. In order to develop the virus resistant crops, a detailed understanding of the molecular interactions between viral and host proteins is necessary. Recessive resistance to a pathogen can be conferred when plant genes essential in the life cycle of a pathogens are deficient, while dominant resistance is mediated by host resistance (R) genes specifically interacting with effector proteins of pathogens. Thus, recessive resistance usually works more stably and broadly than dominant resistance. While most of the recessive resistance genes have so far been identified by forward genetic approaches, recent advances in genome editing technologies including CRISPR/Cas9 have increased interest in using these technologies as reverse genetic tools to engineer plant genes to confer recessive resistance. This review summarizes currently identified recessive resistance genes and introduces reverse genetic approaches to identify host interacting partner proteins of viral proteins and to evaluate the identified genes as genetic resources of recessive resistance. We further discuss recent advances in various precise genome editing technologies and how to apply these technologies to engineer plant immunity." @default.
• W2954249255 created "2019-07-12" @default.
• W2954249255 creator A5000259024 @default.
• W2954249255 creator A5005764211 @default.
• W2954249255 creator A5019778285 @default.
• W2954249255 creator A5054093970 @default.
• W2954249255 date "2019-06-30" @default.
• W2954249255 modified "2023-09-30" @default.
• W2954249255 title "Recessive Resistance: Developing Targets for Genome Editing to Engineer Viral Disease Resistant Crops" @default.
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