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- W2954292606 abstract "Exercise improves sleep and reduces apnea severity in adults with obstructive sleep apnea (OSA). However, whether reducing sedentary behavior impacts sleep and apnea severity is unknown. PURPOSE: To examine whether reducing prolonged sitting during a simulated workday by use of a sit-stand desk leads to changes in sleep compared to a sedentary workday in a sample of adults at high risk for OSA. METHODS: Eight inactive adults (5 males, 53.8±8.5 yr, body mass index: 29.8±5.5 kg/m2) who were classified as ‘high risk’ for OSA based upon the STOP-BANG screening algorithm participated in a randomized crossover trial consisting of two simulated 8-h workdays: (1) continuous sitting (SIT); and (2) alternating periods of sitting and standing every 30 min (SIT-STAND). Sleep and apnea were assessed on the night following each simulated workday by wrist-worn actigraphy and a portable OSA testing device, respectively. Actigraphic measures of total sleep time (TST) and wake after sleep onset (WASO) served as the primary sleep variables, while the apnea-hypopnea index (AHI) assessed OSA severity from the OSA testing device by a blinded assessor. Natural logarithm transformation of AHI was performed due to non-normality. Effect sizes (Hedges’ g) and Pearson correlations evaluated differences in sleep following each condition and associations between changes in sleep measures, respectively. RESULTS: In the full sample, trivial improvements in WASO (g=0.16) and TST (g=0.03) were observed following SIT-STAND compared to SIT. In contrast, a small increase in AHI (i.e., worsening of OSA) was observed following SIT-STAND compared to SIT (g=0.31). The change in AHI was associated with the change in actigraphic WASO (r=.63, P=.09). Four of the 8 adults had clinically significant OSA (i.e., mean AHI≥10 across conditions). Among those with clinically significant OSA, large increases in WASO and AHI were seen following SIT-STAND relative to SIT (g=1.16 and 0.89, respectively). In those without significant OSA, small- to moderate-sized reductions in WASO and AHI were observed following SIT-STAND compared to SIT (g=0.68 and 0.30, respectively). CONCLUSION: Following sedentary behavior reduction during a simulated workday, changes in sleep and apnea seemed to differ based upon the presence of clinically significant OSA." @default.
- W2954292606 created "2019-07-12" @default.
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- W2954292606 date "2019-06-01" @default.
- W2954292606 modified "2023-10-14" @default.
- W2954292606 title "Impact of a Simulated Workday of Sit-stand Desk Use on Sleep Among Adults Screened as High Risk for Sleep Apnea" @default.
- W2954292606 doi "https://doi.org/10.1249/01.mss.0000560833.62028.7b" @default.
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