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- W2954325246 abstract "PURPOSE: Endurance runners training with high-intensity intermittent exercise might experience damage to cardiac muscle. We have therefore compared the changes of cardiac biomarkers after workload-matched intermittent and continuous exercise in such runners. METHODS: Twelve endurance runners (11 males, 1 female; age, 23.5±5.5 y; VO2max, 62.4±5.4 ml.kg−1.min−1; velocity of VO2max [vVO2max], 17.1±1.4 km.h−1; training volume, 44 ± 25 km.wk−1) completed intermittent and continuous exercise trials in random order. Intermittent exercise consisted of hard running at 90% vVO2max for 2 min followed by easy running at 50% vVO2max for 2 min, repeated for 92 min in total. The continuous run was performed at 70% vVO2max for 92 min. Blood samples were drawn before exercise and at 0, 2, 4, 24 and 48 h after the completion of exercise for assay of various cardiac biomarkers. Changes in concentration of each biomarker were averaged over 0-24 h for comparison of intermittent with continuous exercise after adjustment for baseline concentration and exercise intensity expressed as percent of heart-rate reserve (%HRR). RESULTS: There were trivial differences between the changes in concentration adjusted to the mean intensity of 78%HRR for all biomarkers investigated, but at 85%HRR high-sensitivity cardiac troponin-I and high-sensitivity cardiac troponin-T were moderately higher following intermittent exercise (factor mean change ×/÷90% confidence limits: 3.4 ×/÷1.9 and 2.1 ×/÷1.8 respectively). Changes in other cardiac biomarkers at 85%HRR were trivial. CONCLUSIONS: Prolonged intermittent exercise is potentially more damaging to heart muscle than continuous exercise of the same average running speed at higher average heart rates." @default.
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- W2954325246 date "2019-06-01" @default.
- W2954325246 modified "2023-10-18" @default.
- W2954325246 title "Effects Of Matched Intermittent Versus Continuous Exercises On The Changes Of Cardiac Biomarkers" @default.
- W2954325246 doi "https://doi.org/10.1249/01.mss.0000560497.21608.ef" @default.
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