FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2954330237> ?p ?o ?g. }

• W2954330237 endingPage "13" @default.
• W2954330237 startingPage "3" @default.
• W2954330237 abstract "This study aimed to compare serum amyloid processing biomarkers among HIV subtype B (n = 25), HIV subtype C (n = 26), healthy HIV-negative controls (n = 18), and patients with Alzheimer’s disease (AD; n = 24). Immunoassays were used to measure main soluble Aβ isoforms Aβ38, Aβ40, Aβ42, and Aβ-total in serum and cerebrospinal fluid (CSF). People living with HIV (PLWH) and HIV(−) samples, including AD samples, were compared for gender and age, while HIV subtypes were compared for nadir CD4 and plasma viral load suppression. CSF/serum ratios of Aβ40, Aβ42, and Aβ-total were lower in HIV-1C group than in HIV-1B group (p = 0.020, 0.025, and 0.050, respectively). In serum, these biomarkers were comparable. Serum Aβ isoforms were significantly lower in PLWH than in AD. Serum Aβ42 levels in PLWH were decreased compared to those in control group, thus similar to Aβ42 alterations in CSF; these results were different from those observed in AD. Impaired cellular immunity, low CD4 cell count (nadir or current) influences serum Aβ metabolism in HIV-1B but not HIV-1C. However, in PLWH overall, but not in individual HIV subtype groups, greater CD4 recovery, calculated as the difference between current and nadir CD4, correlated with Aβ42/Aβ40 ratio in serum (rs 0.246; p = 0.0479). No significant correlation was found with global deficit score (GDS), an index of neurocognitive performance, age, or duration of infection. These findings are consistent with those of subtype-dependent amyloid processing in blood in chronic HIV disease." @default.
• W2954330237 created "2019-07-12" @default.
• W2954330237 creator A5003954254 @default.
• W2954330237 creator A5025633711 @default.
• W2954330237 creator A5039944358 @default.
• W2954330237 creator A5040325066 @default.
• W2954330237 creator A5044042587 @default.
• W2954330237 creator A5058189092 @default.
• W2954330237 creator A5081172888 @default.
• W2954330237 creator A5084491805 @default.
• W2954330237 creator A5087905290 @default.
• W2954330237 date "2019-07-07" @default.
• W2954330237 modified "2023-10-16" @default.
• W2954330237 title "Blood amyloid-β protein isoforms are affected by HIV-1 in a subtype-dependent pattern" @default.
• W2954330237 cites W1510385670 @default.
• W2954330237 cites W1966613471 @default.
• W2954330237 cites W1971735349 @default.
• W2954330237 cites W1981552723 @default.
• W2954330237 cites W1986063396 @default.
• W2954330237 cites W1986695958 @default.
• W2954330237 cites W1987922097 @default.
• W2954330237 cites W1988476969 @default.
• W2954330237 cites W1992604744 @default.
• W2954330237 cites W1996295012 @default.
• W2954330237 cites W2011552687 @default.
• W2954330237 cites W2017779103 @default.
• W2954330237 cites W2018802516 @default.
• W2954330237 cites W2024353040 @default.
• W2954330237 cites W2024828458 @default.
• W2954330237 cites W2033154907 @default.
• W2954330237 cites W2033265046 @default.
• W2954330237 cites W2038965421 @default.
• W2954330237 cites W2047656594 @default.
• W2954330237 cites W2054450876 @default.
• W2954330237 cites W2055010339 @default.
• W2954330237 cites W2057906523 @default.
• W2954330237 cites W2063806833 @default.
• W2954330237 cites W2064844843 @default.
• W2954330237 cites W2075840970 @default.
• W2954330237 cites W2077459912 @default.
• W2954330237 cites W2079402113 @default.
• W2954330237 cites W2080315478 @default.
• W2954330237 cites W2080432920 @default.
• W2954330237 cites W2087574229 @default.
• W2954330237 cites W2091277662 @default.
• W2954330237 cites W2094777896 @default.
• W2954330237 cites W2096410114 @default.
• W2954330237 cites W2101060023 @default.
• W2954330237 cites W2109135047 @default.
• W2954330237 cites W2110797945 @default.
• W2954330237 cites W2115017507 @default.
• W2954330237 cites W2127108221 @default.
• W2954330237 cites W2127804398 @default.
• W2954330237 cites W2130653534 @default.
• W2954330237 cites W2165503155 @default.
• W2954330237 cites W2196013593 @default.
• W2954330237 cites W2239656194 @default.
• W2954330237 cites W2340076510 @default.
• W2954330237 cites W2410715071 @default.
• W2954330237 cites W2529926589 @default.
• W2954330237 cites W2766946806 @default.
• W2954330237 cites W2775139260 @default.
• W2954330237 cites W2790394987 @default.
• W2954330237 cites W2801801043 @default.
• W2954330237 cites W4247665917 @default.
• W2954330237 cites W4298870098 @default.
• W2954330237 doi "https://doi.org/10.1007/s13365-019-00783-6" @default.
• W2954330237 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6944779" @default.
• W2954330237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31281948" @default.
• W2954330237 hasPublicationYear "2019" @default.
• W2954330237 type Work @default.
• W2954330237 sameAs 2954330237 @default.
• W2954330237 citedByCount "9" @default.
• W2954330237 countsByYear W29543302372020 @default.
• W2954330237 countsByYear W29543302372021 @default.
• W2954330237 countsByYear W29543302372022 @default.
• W2954330237 countsByYear W29543302372023 @default.
• W2954330237 crossrefType "journal-article" @default.
• W2954330237 hasAuthorship W2954330237A5003954254 @default.
• W2954330237 hasAuthorship W2954330237A5025633711 @default.
• W2954330237 hasAuthorship W2954330237A5039944358 @default.
• W2954330237 hasAuthorship W2954330237A5040325066 @default.
• W2954330237 hasAuthorship W2954330237A5044042587 @default.
• W2954330237 hasAuthorship W2954330237A5058189092 @default.
• W2954330237 hasAuthorship W2954330237A5081172888 @default.
• W2954330237 hasAuthorship W2954330237A5084491805 @default.
• W2954330237 hasAuthorship W2954330237A5087905290 @default.
• W2954330237 hasBestOaLocation W29543302372 @default.
• W2954330237 hasConcept C118552586 @default.
• W2954330237 hasConcept C126322002 @default.
• W2954330237 hasConcept C134018914 @default.
• W2954330237 hasConcept C142462285 @default.
• W2954330237 hasConcept C16568411 @default.
• W2954330237 hasConcept C169900460 @default.
• W2954330237 hasConcept C172467417 @default.
• W2954330237 hasConcept C203014093 @default.
• W2954330237 hasConcept C2779651940 @default.
• W2954330237 hasConcept C3013748606 @default.

• next