FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2954333889> ?p ?o ?g. }

• W2954333889 endingPage "51" @default.
• W2954333889 startingPage "46" @default.
• W2954333889 abstract "Our prospective study was therefore designed to determine which part of the systemic inflammatory response after cardiac operations resulted from Cardiopulmonary bypass (CPB) in neonates and infants. After approval by the human ethical committee of the Gunma Children’s Medical Center (GCMC) and informed consent of the parents, 40 consecutive term congenital heart disease patients aged until 1 year who underwent long CPB time (> 3 h) at surgery were included in the prospective study between January 2012 and December 2014. C1 esterase inhibitor (C1-inh) drug (@Berinert) was generously provided by CSL Behring (King of Prussia, PA). The C1-inh (20 IU/kg) was given intravenously 60 min after CPB. Blood samples for complement factors were obtained before and 48 h after administration of C1-inh. Six patients did not survive and their data were not included. Of 34 patients included, median age was 6.5 months, median body weight was 6050 g, and 16 (47%) were female. According to the Mann–Whitney U test, there were no differences between the two groups concerning demographic and intraoperative data, postoperative chemical data. C1q concentration was only significant lower in patients with C1-inh non-treated group than in patients with C1-inh treated group. But, the consumption of C1q, C3, C4, CH50, and C1-inh in patients with C1-inhibitor non-treated group was observed early postoperatively. There is a significant difference in the values before and after C1-inh treatment between the two groups. The lower value in the C1-inh-treated group is explained by the activation of the classical pathway through the replenishment of complements by C1-inh treatment. This study proposes the administration of C1-inh is an effective therapy to reduce the activation and improve the clinical capillary leak syndrome." @default.
• W2954333889 created "2019-07-12" @default.
• W2954333889 creator A5005973012 @default.
• W2954333889 creator A5009220107 @default.
• W2954333889 creator A5012383469 @default.
• W2954333889 creator A5022598189 @default.
• W2954333889 creator A5035157397 @default.
• W2954333889 creator A5038582446 @default.
• W2954333889 date "2019-07-05" @default.
• W2954333889 modified "2023-10-14" @default.
• W2954333889 title "C1 esterase inhibitor in pediatric cardiac surgery with cardiopulmonary bypass plays a vital role in activation of the complement system" @default.
• W2954333889 cites W1969441988 @default.
• W2954333889 cites W1991328941 @default.
• W2954333889 cites W2017392186 @default.
• W2954333889 cites W2041120347 @default.
• W2954333889 cites W2079053397 @default.
• W2954333889 cites W2094468885 @default.
• W2954333889 cites W2104431536 @default.
• W2954333889 cites W2137169303 @default.
• W2954333889 cites W2157402265 @default.
• W2954333889 cites W2168512911 @default.
• W2954333889 doi "https://doi.org/10.1007/s00380-019-01466-2" @default.
• W2954333889 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7223185" @default.
• W2954333889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31278424" @default.
• W2954333889 hasPublicationYear "2019" @default.
• W2954333889 type Work @default.
• W2954333889 sameAs 2954333889 @default.
• W2954333889 citedByCount "6" @default.
• W2954333889 countsByYear W29543338892020 @default.
• W2954333889 countsByYear W29543338892022 @default.
• W2954333889 crossrefType "journal-article" @default.
• W2954333889 hasAuthorship W2954333889A5005973012 @default.
• W2954333889 hasAuthorship W2954333889A5009220107 @default.
• W2954333889 hasAuthorship W2954333889A5012383469 @default.
• W2954333889 hasAuthorship W2954333889A5022598189 @default.
• W2954333889 hasAuthorship W2954333889A5035157397 @default.
• W2954333889 hasAuthorship W2954333889A5038582446 @default.
• W2954333889 hasBestOaLocation W29543338891 @default.
• W2954333889 hasConcept C111684460 @default.
• W2954333889 hasConcept C126322002 @default.
• W2954333889 hasConcept C141071460 @default.
• W2954333889 hasConcept C159654299 @default.
• W2954333889 hasConcept C188816634 @default.
• W2954333889 hasConcept C203014093 @default.
• W2954333889 hasConcept C2778789114 @default.
• W2954333889 hasConcept C2778881276 @default.
• W2954333889 hasConcept C42219234 @default.
• W2954333889 hasConcept C71924100 @default.
• W2954333889 hasConceptScore W2954333889C111684460 @default.
• W2954333889 hasConceptScore W2954333889C126322002 @default.
• W2954333889 hasConceptScore W2954333889C141071460 @default.
• W2954333889 hasConceptScore W2954333889C159654299 @default.
• W2954333889 hasConceptScore W2954333889C188816634 @default.
• W2954333889 hasConceptScore W2954333889C203014093 @default.
• W2954333889 hasConceptScore W2954333889C2778789114 @default.
• W2954333889 hasConceptScore W2954333889C2778881276 @default.
• W2954333889 hasConceptScore W2954333889C42219234 @default.
• W2954333889 hasConceptScore W2954333889C71924100 @default.
• W2954333889 hasIssue "1" @default.
• W2954333889 hasLocation W29543338891 @default.
• W2954333889 hasLocation W29543338892 @default.
• W2954333889 hasLocation W29543338893 @default.
• W2954333889 hasLocation W29543338894 @default.
• W2954333889 hasOpenAccess W2954333889 @default.
• W2954333889 hasPrimaryLocation W29543338891 @default.
• W2954333889 hasRelatedWork W1970526206 @default.
• W2954333889 hasRelatedWork W2021776879 @default.
• W2954333889 hasRelatedWork W2027280171 @default.
• W2954333889 hasRelatedWork W2049733093 @default.
• W2954333889 hasRelatedWork W2078954508 @default.
• W2954333889 hasRelatedWork W2120795994 @default.
• W2954333889 hasRelatedWork W2137909243 @default.
• W2954333889 hasRelatedWork W2332506018 @default.
• W2954333889 hasRelatedWork W2383118485 @default.
• W2954333889 hasRelatedWork W3129089517 @default.
• W2954333889 hasVolume "35" @default.
• W2954333889 isParatext "false" @default.
• W2954333889 isRetracted "false" @default.
• W2954333889 magId "2954333889" @default.
• W2954333889 workType "article" @default.