FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2954409411> ?p ?o ?g. }

• W2954409411 abstract "The present study demonstrates the use of self-assembled nanostructures of cationic amphiphilic azobenzene-neomycin (a small molecule) conjugate, Azo-Neo, as delivery vector for plasmid DNA. These nanostructures efficiently condensed nucleic acid and formed more compact nanoassemblies. DLS analysis showed size and zeta potential of the resulting Azo-Neo/pDNA nanoassemblies ∼153.7nm and +7.26mV, respectively. The nanoassemblies were characterized by physicochemical techniques and evaluated for its toxicity and ability to deliver nucleic acid therapeutics. The flow cytometry results on MCF-7 and HEK293T cells revealed that Azo-Neo/pDNA nanoassemblies transfected ∼31% and 23% cells, respectively, at a w/w ratio of 250, while the standard transfection reagent, bPEI/pDNA complex, could transfect only ∼21% and 29% cells, respectively, at its best w:w ratio of 2.3. MTT and hemolysis assays showed the non-toxic nature of the projected nanoassemblies and nanostructures, respectively, at various concentrations. Further, Azo-Neo nanostructures showed efficient antibacterial activity against different strains, laboratory strain of Staphylococcus aureus (MTCC 740) as well as MRSA strains (Staphylococcus aureus ATCC 33591, ATCC 43300 and ATCC 700699). These results ensure the great potential of these nanostructures in gene delivery and antimicrobial applications." @default.
• W2954409411 created "2019-07-12" @default.
• W2954409411 creator A5011801403 @default.
• W2954409411 creator A5026996660 @default.
• W2954409411 creator A5040921635 @default.
• W2954409411 creator A5069317267 @default.
• W2954409411 creator A5082658259 @default.
• W2954409411 date "2016-01-01" @default.
• W2954409411 modified "2023-09-28" @default.
• W2954409411 title "Amphiphilic azobenzene-neomycin conjugate self-assembles into nanostructures and transports plasmid DNA efficiently into the mammalian cells B Biointerfaces" @default.
• W2954409411 hasPublicationYear "2016" @default.
• W2954409411 type Work @default.
• W2954409411 sameAs 2954409411 @default.
• W2954409411 citedByCount "0" @default.
• W2954409411 crossrefType "journal-article" @default.
• W2954409411 hasAuthorship W2954409411A5011801403 @default.
• W2954409411 hasAuthorship W2954409411A5026996660 @default.
• W2954409411 hasAuthorship W2954409411A5040921635 @default.
• W2954409411 hasAuthorship W2954409411A5069317267 @default.
• W2954409411 hasAuthorship W2954409411A5082658259 @default.
• W2954409411 hasConcept C104317684 @default.
• W2954409411 hasConcept C12554922 @default.
• W2954409411 hasConcept C134306372 @default.
• W2954409411 hasConcept C135983454 @default.
• W2954409411 hasConcept C155672457 @default.
• W2954409411 hasConcept C15920480 @default.
• W2954409411 hasConcept C171250308 @default.
• W2954409411 hasConcept C178790620 @default.
• W2954409411 hasConcept C183882617 @default.
• W2954409411 hasConcept C185592680 @default.
• W2954409411 hasConcept C192562407 @default.
• W2954409411 hasConcept C197336794 @default.
• W2954409411 hasConcept C202751555 @default.
• W2954409411 hasConcept C21951064 @default.
• W2954409411 hasConcept C22744801 @default.
• W2954409411 hasConcept C24107716 @default.
• W2954409411 hasConcept C2778150588 @default.
• W2954409411 hasConcept C2779489039 @default.
• W2954409411 hasConcept C2779841869 @default.
• W2954409411 hasConcept C2780783641 @default.
• W2954409411 hasConcept C32909587 @default.
• W2954409411 hasConcept C33923547 @default.
• W2954409411 hasConcept C501593827 @default.
• W2954409411 hasConcept C521977710 @default.
• W2954409411 hasConcept C523546767 @default.
• W2954409411 hasConcept C54009773 @default.
• W2954409411 hasConcept C54355233 @default.
• W2954409411 hasConcept C552990157 @default.
• W2954409411 hasConcept C55493867 @default.
• W2954409411 hasConcept C67407626 @default.
• W2954409411 hasConcept C86181022 @default.
• W2954409411 hasConcept C86803240 @default.
• W2954409411 hasConceptScore W2954409411C104317684 @default.
• W2954409411 hasConceptScore W2954409411C12554922 @default.
• W2954409411 hasConceptScore W2954409411C134306372 @default.
• W2954409411 hasConceptScore W2954409411C135983454 @default.
• W2954409411 hasConceptScore W2954409411C155672457 @default.
• W2954409411 hasConceptScore W2954409411C15920480 @default.
• W2954409411 hasConceptScore W2954409411C171250308 @default.
• W2954409411 hasConceptScore W2954409411C178790620 @default.
• W2954409411 hasConceptScore W2954409411C183882617 @default.
• W2954409411 hasConceptScore W2954409411C185592680 @default.
• W2954409411 hasConceptScore W2954409411C192562407 @default.
• W2954409411 hasConceptScore W2954409411C197336794 @default.
• W2954409411 hasConceptScore W2954409411C202751555 @default.
• W2954409411 hasConceptScore W2954409411C21951064 @default.
• W2954409411 hasConceptScore W2954409411C22744801 @default.
• W2954409411 hasConceptScore W2954409411C24107716 @default.
• W2954409411 hasConceptScore W2954409411C2778150588 @default.
• W2954409411 hasConceptScore W2954409411C2779489039 @default.
• W2954409411 hasConceptScore W2954409411C2779841869 @default.
• W2954409411 hasConceptScore W2954409411C2780783641 @default.
• W2954409411 hasConceptScore W2954409411C32909587 @default.
• W2954409411 hasConceptScore W2954409411C33923547 @default.
• W2954409411 hasConceptScore W2954409411C501593827 @default.
• W2954409411 hasConceptScore W2954409411C521977710 @default.
• W2954409411 hasConceptScore W2954409411C523546767 @default.
• W2954409411 hasConceptScore W2954409411C54009773 @default.
• W2954409411 hasConceptScore W2954409411C54355233 @default.
• W2954409411 hasConceptScore W2954409411C552990157 @default.
• W2954409411 hasConceptScore W2954409411C55493867 @default.
• W2954409411 hasConceptScore W2954409411C67407626 @default.
• W2954409411 hasConceptScore W2954409411C86181022 @default.
• W2954409411 hasConceptScore W2954409411C86803240 @default.
• W2954409411 hasLocation W29544094111 @default.
• W2954409411 hasOpenAccess W2954409411 @default.
• W2954409411 hasPrimaryLocation W29544094111 @default.
• W2954409411 hasRelatedWork W1984432487 @default.
• W2954409411 hasRelatedWork W1985938464 @default.
• W2954409411 hasRelatedWork W1995014354 @default.
• W2954409411 hasRelatedWork W2007699408 @default.
• W2954409411 hasRelatedWork W2008373918 @default.
• W2954409411 hasRelatedWork W2027340393 @default.
• W2954409411 hasRelatedWork W2038009048 @default.
• W2954409411 hasRelatedWork W2039577598 @default.
• W2954409411 hasRelatedWork W2132286730 @default.
• W2954409411 hasRelatedWork W2201498990 @default.
• W2954409411 hasRelatedWork W2319118173 @default.
• W2954409411 hasRelatedWork W2349784298 @default.
• W2954409411 hasRelatedWork W2408258159 @default.

• next