FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2954521113> ?p ?o ?g. }

• W2954521113 endingPage "e0219063" @default.
• W2954521113 startingPage "e0219063" @default.
• W2954521113 abstract "Propolis is a complex mixture of resinous and balsamic material collected from the exudates of plants, shoots, and leaves by bees. This study evaluated red propolis extracts obtained by conventional (ethanolic) extraction and ultrasound-assisted extraction of six samples from different regions of northeastern Brazil. The total phenolic compounds and flavonoids, in vitro antioxidant activity, concentration of formononetin and kaempferol and the cytotoxicity against four human tumor cell lines were determined for all twelve obtained extracts. Significant variations in the levels of the investigated compounds were identified in the red propolis extracts, confirming that the chemical composition varied according to the sampling region. The extraction method used also influenced the resulting propolis compounds. The highest concentration of the compounds of interest and the highest in vitro antioxidant activity were exhibited by the extracts obtained from samples from state of Alagoas. Formononetin and kaempferol were identified in all samples. The highest formononetin concentrations were identified in extracts obtained by ultrasound, thus indicating a greater selectivity for the extraction of this compound by this method. Regarding cytotoxic activity, for the HCT-116 line, all of the extracts showed an inhibition of greater than 90%, whereas for the HL-60 and PC3 lines, the minimum identified was 80%. In general, there was no significant difference (p>0.05) in the antiproliferative potential when comparing the extraction methods. The results showed that the composition of Brazilian red propolis varies significantly depending on the geographical origin and that the method used influences the resulting compounds that are present in propolis. However, regardless of the geographical origin and the extraction method used, all the red propolis samples studied presented great biological potential and high antioxidant activity. Furthermore, the ultrasound-assisted method can be efficiently applied to obtain extracts of red propolis more quickly and with high concentration of biomarkers of interest." @default.
• W2954521113 created "2019-07-12" @default.
• W2954521113 creator A5003128296 @default.
• W2954521113 creator A5011327984 @default.
• W2954521113 creator A5014755520 @default.
• W2954521113 creator A5018045516 @default.
• W2954521113 creator A5044050628 @default.
• W2954521113 creator A5054266283 @default.
• W2954521113 creator A5069988304 @default.
• W2954521113 creator A5075793136 @default.
• W2954521113 date "2019-07-05" @default.
• W2954521113 modified "2023-10-17" @default.
• W2954521113 title "Evaluation of the antioxidant profile and cytotoxic activity of red propolis extracts from different regions of northeastern Brazil obtained by conventional and ultrasound-assisted extraction" @default.
• W2954521113 cites W1152422006 @default.
• W2954521113 cites W1277054846 @default.
• W2954521113 cites W1559903407 @default.
• W2954521113 cites W1675557712 @default.
• W2954521113 cites W1921620236 @default.
• W2954521113 cites W1965361476 @default.
• W2954521113 cites W1972155313 @default.
• W2954521113 cites W1972840169 @default.
• W2954521113 cites W1978791478 @default.
• W2954521113 cites W1982728274 @default.
• W2954521113 cites W1984228207 @default.
• W2954521113 cites W1985391300 @default.
• W2954521113 cites W1985470643 @default.
• W2954521113 cites W1986326192 @default.
• W2954521113 cites W1994724667 @default.
• W2954521113 cites W1998706604 @default.
• W2954521113 cites W1998851516 @default.
• W2954521113 cites W1999244760 @default.
• W2954521113 cites W1999288447 @default.
• W2954521113 cites W2000613531 @default.
• W2954521113 cites W2001766416 @default.
• W2954521113 cites W2003917450 @default.
• W2954521113 cites W2006581725 @default.
• W2954521113 cites W2008045574 @default.
• W2954521113 cites W2009673853 @default.
• W2954521113 cites W2012634891 @default.
• W2954521113 cites W2013798382 @default.
• W2954521113 cites W2024061519 @default.
• W2954521113 cites W2024183118 @default.
• W2954521113 cites W2024682916 @default.
• W2954521113 cites W2025235228 @default.
• W2954521113 cites W2025456365 @default.
• W2954521113 cites W2025521300 @default.
• W2954521113 cites W2028977508 @default.
• W2954521113 cites W2032905041 @default.
• W2954521113 cites W2034131386 @default.
• W2954521113 cites W2034596339 @default.
• W2954521113 cites W2037399744 @default.
• W2954521113 cites W2040270316 @default.
• W2954521113 cites W2041351646 @default.
• W2954521113 cites W2042914049 @default.
• W2954521113 cites W2043428504 @default.
• W2954521113 cites W2047261980 @default.
• W2954521113 cites W2048396021 @default.
• W2954521113 cites W2054206661 @default.
• W2954521113 cites W2060530792 @default.
• W2954521113 cites W2062194604 @default.
• W2954521113 cites W2064338251 @default.
• W2954521113 cites W2065082951 @default.
• W2954521113 cites W2065140801 @default.
• W2954521113 cites W2065853716 @default.
• W2954521113 cites W2072435855 @default.
• W2954521113 cites W2073045932 @default.
• W2954521113 cites W2073941571 @default.
• W2954521113 cites W2074296866 @default.
• W2954521113 cites W2075264042 @default.
• W2954521113 cites W2076941943 @default.
• W2954521113 cites W2077536680 @default.
• W2954521113 cites W2077674819 @default.
• W2954521113 cites W2080411331 @default.
• W2954521113 cites W2080920409 @default.
• W2954521113 cites W2084609755 @default.
• W2954521113 cites W2088533523 @default.
• W2954521113 cites W2089290870 @default.
• W2954521113 cites W2090448134 @default.
• W2954521113 cites W2091553871 @default.
• W2954521113 cites W2095211286 @default.
• W2954521113 cites W2101941667 @default.
• W2954521113 cites W2103666387 @default.
• W2954521113 cites W2109625220 @default.
• W2954521113 cites W2111195206 @default.
• W2954521113 cites W2114004260 @default.
• W2954521113 cites W2114918609 @default.
• W2954521113 cites W2118940054 @default.
• W2954521113 cites W2119374620 @default.
• W2954521113 cites W2123840690 @default.
• W2954521113 cites W2127999352 @default.
• W2954521113 cites W2130631177 @default.
• W2954521113 cites W2133599412 @default.
• W2954521113 cites W2140427876 @default.
• W2954521113 cites W2142736475 @default.
• W2954521113 cites W2143256251 @default.
• W2954521113 cites W2143525532 @default.
• W2954521113 cites W2146992149 @default.
• W2954521113 cites W2151320943 @default.

• next