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- W2954554062 abstract "A sensitive zero order UV spectroscopic method (Method A) and a first order derivative method (Method B) has been developed and validated for the determination of Itraconazole in formulations using phosphate buffer (pH 2.0). The drug showed maximum absorbance at 255nm (Method A) and amplitude was measured in the range of 245 nm-270 nm (Method B). Thedrug obeyed linearity in the range of 5–60 μg/mL. The present methods were validated as per International Conference on Harmonization guidelines. Percent recovery for Itraconazole in the range of 98- 101.66 % indicates accuracy and % RSD < 1.95 indicates precision of the methods. These methods can beconveniently used for the quality control analysis of Itraconazole in capsules without any interference from the excipients." @default.
- W2954554062 created "2019-07-12" @default.
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- W2954554062 date "2019-02-12" @default.
- W2954554062 modified "2023-10-16" @default.
- W2954554062 title "UV Spectrophotometric Method Development and Validation for Determination of an Antifungal Agent in Bulk and Capsules" @default.
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- W2954554062 doi "https://doi.org/10.5281/zenodo.2562399" @default.
- W2954554062 hasPublicationYear "2019" @default.
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