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• W2954651671 endingPage "140" @default.
• W2954651671 startingPage "123" @default.
• W2954651671 abstract "Malaria continues to be a global health burden, threatening over 40% of the world's population. Drug resistance in Plasmodium falciparum, the etiological agent of the majority of human malaria cases, is compromising elimination efforts. New approaches to treating drug-resistant malaria benefit from defining resistance liabilities of known antimalarial agents and compounds in development and defining genetic changes that mediate loss of parasite susceptibility. Here, we present protocols for in vitro selection of drug-resistant parasites and for site-directed gene editing of candidate resistance mediators to test for causality." @default.
• W2954651671 created "2019-07-12" @default.
• W2954651671 creator A5069436445 @default.
• W2954651671 creator A5071314941 @default.
• W2954651671 date "2019-01-01" @default.
• W2954651671 modified "2023-10-02" @default.
• W2954651671 title "Plasmodium falciparum In Vitro Drug Resistance Selections and Gene Editing" @default.
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• W2954651671 doi "https://doi.org/10.1007/978-1-4939-9550-9_9" @default.
• W2954651671 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6756925" @default.
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• W2954651671 hasPublicationYear "2019" @default.
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