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- W2954653485 abstract "Exosomes were first described as waste carriers implicated in reticulocyte maturation but has during the past decade been associated with many other cellular functions. The biogenesis of exosomes has been extensively studied and several protein machineries have been identified to dictate their production and release. The newly discovered branches of the autophagy system implicate secretion of waste in endosomal-derived vesicles as is thought for exosome release. Many of the proteins that have been identified as responsible for the formation and release of these vesicles are the same as those identified in exosome biogenesis. In this Perspective, we discuss the possibility of exosomes being a part of the autophagy machinery and the consequences this could have on interpretation of exosome functions." @default.
- W2954653485 created "2019-07-12" @default.
- W2954653485 creator A5018117774 @default.
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- W2954653485 date "2019-06-06" @default.
- W2954653485 modified "2023-10-14" @default.
- W2954653485 title "Exosomes and autophagy: rekindling the vesicular waste hypothesis" @default.
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- W2954653485 doi "https://doi.org/10.1007/s12079-019-00524-8" @default.
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