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- W2954698749 abstract "Microvascular remodeling, or angiogenesis, plays a central role in multiple pathological conditions, including cancer, diabetes, and ischemia. Tissue-engineered in vitro models have emerged as tools to elucidate the mechanisms that drive the angiogenic process. However, a major challenge with model development is recapitulating the physiological complexity of real microvascular networks, including incorporation of the entire vascular tree and hemodynamics. This study establishes a bioreactor system that incorporates real microvascular networks with physiological flow as a novel ex vivo tissue culture model, thereby providing a platform to evaluate angiogenesis in a physiologically relevant environment." @default.
- W2954698749 created "2019-07-12" @default.
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- W2954698749 date "2019-08-01" @default.
- W2954698749 modified "2023-10-14" @default.
- W2954698749 title "Bioreactor System to Perfuse Mesentery Microvascular Networks and Study Flow Effects During Angiogenesis" @default.
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- W2954698749 doi "https://doi.org/10.1089/ten.tec.2019.0119" @default.
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