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- W2954804537 abstract "Introduction: The histologic pattern of esophageal cancer has changed dramatically in Western countries over the last two decades. Up to this day, tumor characteristics of esophageal cancers in the Mexican population have not been reported in the English literature Methods: We performed a retrospective analysis of patients with newly diagnosed esophageal cancer treated at an oncology referral center in North-East Mexico from 2013 to 2017. Results: Seventy-six patients were included in the analysis. Mean age at diagnosis was 64.7 ± 12.1 years, 81.6% were men. Mean BMI was 23.8 ± 4.29 kg/m2 and a ECOG PS 0-2 was found in 85% of cases. Sixty percent of all esophageal tumors analyzed were adenocarcinoma, 39% squamous cell carcinoma (SCC), and 1% undifferentiated carcinoma. Seventy-one percent of patients presented with locoregional disease (CS I-III) and 29% were classified as stage IV disease on their first assessment. Primary tumor location was as follows: Lower-third 38%, gastroesophageal junction 26%, upper-third 19%, and middle-third 17%. Tumors were classified as grade I, II and III in 8%, 55% and 37% of cases, respectively. Among the main risk factors present in our population, tobacco and alcohol consumption were present in 48% and 56% of patients, respectively. A history of gastro-esophageal reflux disease (GERD) and diagnosis of Barret’s esophagus was reported in 23% and 8% of cases, respectively. Conclusion: To our knowledge, this is the first study analyzing the clinical-pathological characteristics of esophageal cancer in the Mexican population. While most of the data presented matches that reported by other authors, some interesting differences unique to our population were observed." @default.
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- W2954804537 date "2019-07-01" @default.
- W2954804537 modified "2023-09-28" @default.
- W2954804537 title "Esophageal cancer: 5 years of experience in a Mexican oncology reference center" @default.
- W2954804537 doi "https://doi.org/10.1093/annonc/mdz155.069" @default.
- W2954804537 hasPublicationYear "2019" @default.
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