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- W2954915511 abstract "Background: 1,4-Diazepines are two nitrogen containing seven membered heterocyclic compounds and associated with a wide range of biological activities. Due to its medicinal importance, scientists are actively involved in the synthesis, reactions and biological evaluation of 1,4-diazepines since number of decades. Objective: The primary purpose of this review is to discuss the synthetic schemes and reactivity of 1,4- diazepines. This article also describes biological aspects of 1,4-diazepine derivatives, that can be usefully exploited for the pharmaceutical sector. Conclusion: This review summarizes the abundant literature on synthetic routes, chemical reactions and biological attributes of 1,4-diazepine derivatives. We concluded that 1,4-diazepines have significant importance due to their biological activities like antipsychotic, anxiolytic, anthelmintic, anticonvulsant, antibacterial, antifungal and anticancer. 1,4-diazepine derivatives with significant biological activities could be explored for potential use in the pharmaceutical industries." @default.
- W2954915511 created "2019-07-12" @default.
- W2954915511 creator A5003411539 @default.
- W2954915511 creator A5020859012 @default.
- W2954915511 creator A5022129540 @default.
- W2954915511 creator A5025092815 @default.
- W2954915511 creator A5048549301 @default.
- W2954915511 creator A5079193184 @default.
- W2954915511 date "2019-10-17" @default.
- W2954915511 modified "2023-10-01" @default.
- W2954915511 title "1,4-Diazepines: A Review on Synthesis, Reactions and Biological Significance" @default.
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