FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2954920208> ?p ?o ?g. }

• W2954920208 endingPage "4" @default.
• W2954920208 startingPage "4" @default.
• W2954920208 abstract "Tylophora indica (Burm. f.) Merr. commonly known as ananthamool is a climbing perennial plant which is widely used in Indian traditional medicine. T. indica exhibits diverse range of pharmacological activities viz. antiasthmatic, antidiarrheal, anticancer, antiarthritic, antiepileptic, anti-inflammatory etc.Present review aims to grant an up-to-date insight into the botany, ethnopharmacology, phytochemistry, pharmacology and toxicology of T. indica, exploring its future research and opportunities.Comprehensive information regarding T. indica was collected using the keywords Tylophora indica or Indian ipecac or ananthamool in various electronic databases ACS, Google Scholar, Pubmed, Science Direct, SciFinder, Web of Science, Springer Link and Wiley. In addition, some books and book chapters were also consulted.T. indica has been traditionally used in India, Bangladesh and Sri Lanka in the form of various preparations like powder, decoction, pulp, paste and extract alone or in combination with other herbs against various ailments like skin disorders, inflammation, cough, asthma, diarrhea, cancer, microbial infections etc. In vitro and in vivo pharmacological studies on T. indica revealed its potential as antiasthmatic, antiallergic, anti-inflammatory, anticancer, antimicrobial, antioxidant, antidiarrheal agent etc. A diverse range of phytochemical constituents have been isolated and identified from T. indica namely alkaloids (Tylophorine, Tylophorinine, Tylophorinidine), flavonoids (Kaempferol & Quercetin) terpenoids (α-Amyrin & β-Amyrin) and sterols (β-sitosetrol). Amongst which phenanthroindolizidine alkaloids isolated from roots and leaves are largely explored and considered to be the most active constituent of plant.Present review provides an insight into botany, ethnopharmacology, phytochemistry, pharmacology and toxicology of T. indica. As an important traditional Indian medicine, few ethnobotanicals use of T. indica have been supported by modern pharmacological studies, especially in asthma, cancer and inflammation. Among compounds from various phytochemical classes, phenanthoindolizidine alkaloids namely tylophorine and tylophorinidine alkaloids have been considered as bioactive components of the plant and widely investigated. However, further identification, isolation and quantification employing some advanced hyphenated techniques viz. LC-MS/MS, LC-NMR to discover new pharmacologically active phytoconstituents in the management of different diseases. Several investigators have highlighted possible therapeutic roles of T. indica extracts and isolated compounds. Moreover, information about various aspects of T. indica pertaining to phytochemistry, toxicology and quality control are still unresolved. Further in-depth studies are required to discover key features viz. structure activity relationships, mode of action, safety and toxicity and therapeutic potentials T. indica in clinical settings." @default.
• W2954920208 created "2019-07-12" @default.
• W2954920208 creator A5007347314 @default.
• W2954920208 date "2019-07-01" @default.
• W2954920208 modified "2023-09-23" @default.
• W2954920208 title "Taking inspiration from how fruitflies smell" @default.
• W2954920208 doi "https://doi.org/10.1016/j.mattod.2019.05.009" @default.
• W2954920208 hasPublicationYear "2019" @default.
• W2954920208 type Work @default.
• W2954920208 sameAs 2954920208 @default.
• W2954920208 citedByCount "0" @default.
• W2954920208 crossrefType "journal-article" @default.
• W2954920208 hasAuthorship W2954920208A5007347314 @default.
• W2954920208 hasConcept C195475562 @default.
• W2954920208 hasConcept C206103511 @default.
• W2954920208 hasConcept C2777810353 @default.
• W2954920208 hasConcept C2778004101 @default.
• W2954920208 hasConcept C2781263971 @default.
• W2954920208 hasConcept C523307889 @default.
• W2954920208 hasConcept C55493867 @default.
• W2954920208 hasConcept C556039675 @default.
• W2954920208 hasConcept C59822182 @default.
• W2954920208 hasConcept C71924100 @default.
• W2954920208 hasConcept C86803240 @default.
• W2954920208 hasConceptScore W2954920208C195475562 @default.
• W2954920208 hasConceptScore W2954920208C206103511 @default.
• W2954920208 hasConceptScore W2954920208C2777810353 @default.
• W2954920208 hasConceptScore W2954920208C2778004101 @default.
• W2954920208 hasConceptScore W2954920208C2781263971 @default.
• W2954920208 hasConceptScore W2954920208C523307889 @default.
• W2954920208 hasConceptScore W2954920208C55493867 @default.
• W2954920208 hasConceptScore W2954920208C556039675 @default.
• W2954920208 hasConceptScore W2954920208C59822182 @default.
• W2954920208 hasConceptScore W2954920208C71924100 @default.
• W2954920208 hasConceptScore W2954920208C86803240 @default.
• W2954920208 hasLocation W29549202081 @default.
• W2954920208 hasOpenAccess W2954920208 @default.
• W2954920208 hasPrimaryLocation W29549202081 @default.
• W2954920208 hasRelatedWork W162845692 @default.
• W2954920208 hasRelatedWork W1844465342 @default.
• W2954920208 hasRelatedWork W2549128777 @default.
• W2954920208 hasRelatedWork W2604529595 @default.
• W2954920208 hasRelatedWork W2898596381 @default.
• W2954920208 hasRelatedWork W2946618205 @default.
• W2954920208 hasRelatedWork W3170317501 @default.
• W2954920208 hasRelatedWork W3192815398 @default.
• W2954920208 hasRelatedWork W4379178889 @default.
• W2954920208 hasRelatedWork W2409977817 @default.
• W2954920208 hasVolume "27" @default.
• W2954920208 isParatext "false" @default.
• W2954920208 isRetracted "false" @default.
• W2954920208 magId "2954920208" @default.
• W2954920208 workType "article" @default.