Matches in SemOpenAlex for { <https://semopenalex.org/work/W2954927143> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2954927143 abstract "Objective: Candidal adherence to denture acrylic surfaces (DAS) and oral buccal epithelial cells (BEC), formation of candidal germ tubes (GT), candidal cell surface hydrophobicity (CSH), and hemolysin production are important pathogenic traits of Candida. The antifungal drug-induced post-antifungal effect (PAFE) also impacts the virulence of Candida. Candida dubliniensis isolates are associated with the causation of oral candidiasis which could be managed with posaconazole. Thus far there is no evidence on posaconazole-induced PAFE and its impact on adhesion-related attributes and production of hemolysin by C. dubliniensis isolates. Hence, the PAFE, adhesion to DAS and BEC, formation of GT, CSH, and hemolysin production of 20 oral C. dubliniensis isolates after brief exposure to posaconazole was ascertained. Materials and Methods: The PAFE, adherence to DAS and BEC, formation of GT, candidal CSH, and hemolysin production were investigated by hitherto described in vitro assays. Results: The mean PAFE (h) induced by posaconazole on C. dubliniensis isolates was 1.66. Exposure to posaconazole suppressed the ability of C. dubliniensis to adhere to DAS, BEC, formation of candidal GT, candidal CSH and to produce hemolysin by a reduction of 44, 33, 34, 36, and 15% (p < 0.005 to p < 0.001), respectively. Conclusion: Exposure of C. dubliniensis isolates to posaconazole for a brief period induced an antimycotic impact by subduing its growth in addition to suppressing pathogenic adherence-associated attributes, as well as production of hemolysin." @default.
- W2954927143 created "2019-07-12" @default.
- W2954927143 creator A5037446038 @default.
- W2954927143 creator A5048120361 @default.
- W2954927143 creator A5082579429 @default.
- W2954927143 date "2019-01-01" @default.
- W2954927143 modified "2023-09-28" @default.
- W2954927143 title "In vitro Post-Antifungal Effect of Posaconazole and Its Impact on Adhesion-Related Traits and Hemolysin Production of Oral Candida dubliniensis Isolates" @default.
- W2954927143 cites W1446232821 @default.
- W2954927143 cites W1570303890 @default.
- W2954927143 cites W1835351127 @default.
- W2954927143 cites W1912420106 @default.
- W2954927143 cites W1940720973 @default.
- W2954927143 cites W1965711485 @default.
- W2954927143 cites W1975324254 @default.
- W2954927143 cites W1991542258 @default.
- W2954927143 cites W1993002865 @default.
- W2954927143 cites W2010467546 @default.
- W2954927143 cites W2014513665 @default.
- W2954927143 cites W2016962061 @default.
- W2954927143 cites W2033788533 @default.
- W2954927143 cites W2035347255 @default.
- W2954927143 cites W2036680967 @default.
- W2954927143 cites W2066142578 @default.
- W2954927143 cites W2070472630 @default.
- W2954927143 cites W2087434904 @default.
- W2954927143 cites W2091760781 @default.
- W2954927143 cites W2108600384 @default.
- W2954927143 cites W2115834673 @default.
- W2954927143 cites W2117018519 @default.
- W2954927143 cites W2122028399 @default.
- W2954927143 cites W2129268728 @default.
- W2954927143 cites W2147398907 @default.
- W2954927143 cites W2150766932 @default.
- W2954927143 cites W2159353442 @default.
- W2954927143 cites W2159518157 @default.
- W2954927143 cites W2166123836 @default.
- W2954927143 cites W2169952036 @default.
- W2954927143 doi "https://doi.org/10.1159/000501764" @default.
- W2954927143 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6944866" @default.
- W2954927143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31247626" @default.
- W2954927143 hasPublicationYear "2019" @default.
- W2954927143 type Work @default.
- W2954927143 sameAs 2954927143 @default.
- W2954927143 citedByCount "2" @default.
- W2954927143 countsByYear W29549271432022 @default.
- W2954927143 crossrefType "journal-article" @default.
- W2954927143 hasAuthorship W2954927143A5037446038 @default.
- W2954927143 hasAuthorship W2954927143A5048120361 @default.
- W2954927143 hasAuthorship W2954927143A5082579429 @default.
- W2954927143 hasBestOaLocation W29549271431 @default.
- W2954927143 hasConcept C104317684 @default.
- W2954927143 hasConcept C136139683 @default.
- W2954927143 hasConcept C145081991 @default.
- W2954927143 hasConcept C2776445003 @default.
- W2954927143 hasConcept C2778566413 @default.
- W2954927143 hasConcept C2779548794 @default.
- W2954927143 hasConcept C2779629538 @default.
- W2954927143 hasConcept C55493867 @default.
- W2954927143 hasConcept C60987743 @default.
- W2954927143 hasConcept C86803240 @default.
- W2954927143 hasConcept C89423630 @default.
- W2954927143 hasConceptScore W2954927143C104317684 @default.
- W2954927143 hasConceptScore W2954927143C136139683 @default.
- W2954927143 hasConceptScore W2954927143C145081991 @default.
- W2954927143 hasConceptScore W2954927143C2776445003 @default.
- W2954927143 hasConceptScore W2954927143C2778566413 @default.
- W2954927143 hasConceptScore W2954927143C2779548794 @default.
- W2954927143 hasConceptScore W2954927143C2779629538 @default.
- W2954927143 hasConceptScore W2954927143C55493867 @default.
- W2954927143 hasConceptScore W2954927143C60987743 @default.
- W2954927143 hasConceptScore W2954927143C86803240 @default.
- W2954927143 hasConceptScore W2954927143C89423630 @default.
- W2954927143 hasLocation W29549271431 @default.
- W2954927143 hasLocation W29549271432 @default.
- W2954927143 hasLocation W29549271433 @default.
- W2954927143 hasLocation W29549271434 @default.
- W2954927143 hasOpenAccess W2954927143 @default.
- W2954927143 hasPrimaryLocation W29549271431 @default.
- W2954927143 hasRelatedWork W1992393617 @default.
- W2954927143 hasRelatedWork W2063390711 @default.
- W2954927143 hasRelatedWork W2070861427 @default.
- W2954927143 hasRelatedWork W2124916048 @default.
- W2954927143 hasRelatedWork W2147968648 @default.
- W2954927143 hasRelatedWork W2168998024 @default.
- W2954927143 hasRelatedWork W2588678479 @default.
- W2954927143 hasRelatedWork W2763904592 @default.
- W2954927143 hasRelatedWork W2954927143 @default.
- W2954927143 hasRelatedWork W3126748938 @default.
- W2954927143 isParatext "false" @default.
- W2954927143 isRetracted "false" @default.
- W2954927143 magId "2954927143" @default.
- W2954927143 workType "article" @default.