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- W2954998480 endingPage "111286" @default.
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- W2954998480 abstract "In this work, the synthesis of graphene oxide grafted poly citric acid-γ-Fe2O3 nanocomposite (GO-g-PCA/γ-Fe2O3) with a simple method and its application as a useful negative contrast agent in magnetic resonance imaging was studied. GO was prepared by Mildly method and polymerized with citric acid to produce GO-g-PCA. γ-Fe2O3 nanoparticles were synthesized by co-precipitation method in the size distribution range of 10–25 nm with saturation magnetization (Ms) 21 emu g−1. The nanoparticles encapsulated on GO-g-PCA to produce nanocomposite that showed excellent stability, extra dispersibility, and good superparamagnetic properties with Ms 14 emu g−1. This nanocomposite provided significant contrast enhancement effect in T2 and T2⁎-weighted images with r2 and r2⁎ values 125.63 and 280.85 mM−1 s−1 respectively at 3.0 T. The cytotoxicity evaluation showed no cell toxicity in HCT-116 cell lines even at a high concentration up to 141 μg mL−1 after being treated for 24 h by MTT assay test method." @default.
- W2954998480 created "2019-07-12" @default.
- W2954998480 creator A5004728916 @default.
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- W2954998480 date "2019-10-01" @default.
- W2954998480 modified "2023-10-18" @default.
- W2954998480 title "Synthesis of completely dispersed water soluble functionalized graphene/γ-Fe2O3 nanocomposite and its application as an MRI contrast agent" @default.
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- W2954998480 doi "https://doi.org/10.1016/j.molliq.2019.111286" @default.
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