FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2955001576> ?p ?o ?g. }

• W2955001576 endingPage "143" @default.
• W2955001576 startingPage "143" @default.
• W2955001576 abstract "Structural alterations in fibroelastic components of the penile corpus cavernousum (CC) may impair its compliance, resulting in venous leakage and erectile dysfunction (ED). Our study evaluated the effectiveness of noninvasive two-dimensional shear-wave elastography (2-D SWE) in quantifying penile CC lesions in rabbits with hyperlipidemia-induced ED. A total of 12 New Zealand white rabbits were randomly divided into two groups. Six were fed a high-cholesterol diet containing 2% cholesterol and 8.5% lard for 10 weeks and the other six were fed normal diet as controls. We measured the shear-wave elastic quantitative (SWQ) value of penile CC by 2-D SWE. Erectile function was investigated by intracavernous injection of papaverine, and immunohistochemical (IHC) staining and the western blot analysis to determine the penile CC lesions. After 10 weeks, the SWQ values obtained from penile CC were remarkably higher in the high-cholesterol-fed compared with the control group, and the ΔICP (ICP plateau minus ICP baseline)/MAP (ICP: intracavernous pressure, MAP: mean arterial pressure) was markedly decreased. The IHC staining and western blot revealed extracellular matrix (ECM) accumulation in penile cavernous tissues, and the smooth muscle cell (SMC) phenotypic transition was affected, as indicated by reduced alpha-smooth muscle actin and calponin-1 expression and increased phospho-myosin light chain20 (p-MLC20)/MLC20 and osteopontin expression. Hyperlipidemia resulted in ECM accumulation accompanied with SMC phenotypic transition in penile CC and impaired the erectile function eventually. These might, in turn, lead to variations in the SWQ values. It suggests that 2-D SWE may be a novel, noninvasive and effective approach that distinguishes penile CC lesions secondary to hyperlipidemia from normal." @default.
• W2955001576 created "2019-07-12" @default.
• W2955001576 creator A5018713323 @default.
• W2955001576 creator A5018989202 @default.
• W2955001576 creator A5031182049 @default.
• W2955001576 creator A5050824653 @default.
• W2955001576 creator A5060335470 @default.
• W2955001576 creator A5071773097 @default.
• W2955001576 creator A5086908332 @default.
• W2955001576 date "2019-01-01" @default.
• W2955001576 modified "2023-10-12" @default.
• W2955001576 title "Novel noninvasive quantification of penile corpus cavernosum lesions in hyperlipidemia-induced erectile dysfunction in rabbits by two-dimensional shear-wave elastography" @default.
• W2955001576 cites W1481008844 @default.
• W2955001576 cites W1543887304 @default.
• W2955001576 cites W1824909668 @default.
• W2955001576 cites W1948456557 @default.
• W2955001576 cites W1980593077 @default.
• W2955001576 cites W2025002838 @default.
• W2955001576 cites W2026740190 @default.
• W2955001576 cites W2036237196 @default.
• W2955001576 cites W2040737491 @default.
• W2955001576 cites W2040942287 @default.
• W2955001576 cites W2049684341 @default.
• W2955001576 cites W2077863235 @default.
• W2955001576 cites W2081376188 @default.
• W2955001576 cites W2113029499 @default.
• W2955001576 cites W2124064181 @default.
• W2955001576 cites W2124559568 @default.
• W2955001576 cites W2135586734 @default.
• W2955001576 cites W2159383994 @default.
• W2955001576 cites W2297358297 @default.
• W2955001576 cites W2419652214 @default.
• W2955001576 cites W2463003963 @default.
• W2955001576 cites W2519956669 @default.
• W2955001576 cites W2565531532 @default.
• W2955001576 cites W2585840089 @default.
• W2955001576 cites W2595709438 @default.
• W2955001576 cites W2613669501 @default.
• W2955001576 cites W2522129445 @default.
• W2955001576 doi "https://doi.org/10.4103/aja.aja_78_18" @default.
• W2955001576 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6413550" @default.
• W2955001576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30409958" @default.
• W2955001576 hasPublicationYear "2019" @default.
• W2955001576 type Work @default.
• W2955001576 sameAs 2955001576 @default.
• W2955001576 citedByCount "9" @default.
• W2955001576 countsByYear W29550015762019 @default.
• W2955001576 countsByYear W29550015762020 @default.
• W2955001576 countsByYear W29550015762021 @default.
• W2955001576 countsByYear W29550015762022 @default.
• W2955001576 countsByYear W29550015762023 @default.
• W2955001576 crossrefType "journal-article" @default.
• W2955001576 hasAuthorship W2955001576A5018713323 @default.
• W2955001576 hasAuthorship W2955001576A5018989202 @default.
• W2955001576 hasAuthorship W2955001576A5031182049 @default.
• W2955001576 hasAuthorship W2955001576A5050824653 @default.
• W2955001576 hasAuthorship W2955001576A5060335470 @default.
• W2955001576 hasAuthorship W2955001576A5071773097 @default.
• W2955001576 hasAuthorship W2955001576A5086908332 @default.
• W2955001576 hasBestOaLocation W29550015761 @default.
• W2955001576 hasConcept C104317684 @default.
• W2955001576 hasConcept C105702510 @default.
• W2955001576 hasConcept C126322002 @default.
• W2955001576 hasConcept C126894567 @default.
• W2955001576 hasConcept C134018914 @default.
• W2955001576 hasConcept C142724271 @default.
• W2955001576 hasConcept C185592680 @default.
• W2955001576 hasConcept C2776415932 @default.
• W2955001576 hasConcept C2776952824 @default.
• W2955001576 hasConcept C2777786686 @default.
• W2955001576 hasConcept C2779091943 @default.
• W2955001576 hasConcept C2779929075 @default.
• W2955001576 hasConcept C2781284789 @default.
• W2955001576 hasConcept C55493867 @default.
• W2955001576 hasConcept C555293320 @default.
• W2955001576 hasConcept C71924100 @default.
• W2955001576 hasConceptScore W2955001576C104317684 @default.
• W2955001576 hasConceptScore W2955001576C105702510 @default.
• W2955001576 hasConceptScore W2955001576C126322002 @default.
• W2955001576 hasConceptScore W2955001576C126894567 @default.
• W2955001576 hasConceptScore W2955001576C134018914 @default.
• W2955001576 hasConceptScore W2955001576C142724271 @default.
• W2955001576 hasConceptScore W2955001576C185592680 @default.
• W2955001576 hasConceptScore W2955001576C2776415932 @default.
• W2955001576 hasConceptScore W2955001576C2776952824 @default.
• W2955001576 hasConceptScore W2955001576C2777786686 @default.
• W2955001576 hasConceptScore W2955001576C2779091943 @default.
• W2955001576 hasConceptScore W2955001576C2779929075 @default.
• W2955001576 hasConceptScore W2955001576C2781284789 @default.
• W2955001576 hasConceptScore W2955001576C55493867 @default.
• W2955001576 hasConceptScore W2955001576C555293320 @default.
• W2955001576 hasConceptScore W2955001576C71924100 @default.
• W2955001576 hasIssue "2" @default.
• W2955001576 hasLocation W29550015761 @default.
• W2955001576 hasLocation W29550015762 @default.
• W2955001576 hasLocation W29550015763 @default.
• W2955001576 hasLocation W29550015764 @default.
• W2955001576 hasOpenAccess W2955001576 @default.

• next