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• W29550549 abstract "We present an extension of Felsenstein's algorithm to indel models defined on entire sequences, without the need to condition on one multiple alignment. The algorithm makes use of a generalization from probabilistic substitution matrices to weighted finite-state transducers. Our approach may equivalently be viewed as a probabilistic formulation of progressive multiple sequence alignment, using partial-order graphs to represent ensemble profiles of ancestral sequences. We present a hierarchical stochastic approximation technique which makes this algorithm tractable for alignment analyses of reasonable size." @default.
• W29550549 created "2016-06-24" @default.
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• W29550549 date "2011-03-22" @default.
• W29550549 modified "2023-09-27" @default.
• W29550549 title "An alignment-free generalization to indels of Felsenstein's phylogenetic pruning algorithm" @default.
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