Matches in SemOpenAlex for { <https://semopenalex.org/work/W2955058547> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2955058547 abstract "Glucose 6-phosphate dehydrogenase (G6PD) is a basic antioxidant pathway for erythrocytes, being its deficiency the most common gene mutation worldwide. As breast cancer is one of the most frequent tumors, many of these patients may present with G6PD deficiency prior treatment without notice.We present the case of a woman deficient for G6PD with the diagnosis of Stage IIIB (cT4d cN1 cM0) HER2-enriched early breast cancer.The patient underwent neoadjuvance with trastuzumab and anthracycline-free chemotherapy, based on docetaxel (75 mg/m2, 120 mg) and carboplatin (AUC 5, 560 mg). She did not present hemolytic crisis and no blood transfusions were needed. She achieved a good pathologic response and completed one-year adjuvant trastuzumab without incidences.Although the role of HER2 and trastuzumab in oxidative stress is not yet completely understood, we suggest that trastuzumab may be a suitable agent for treatment in patients with HER2-enriched breast cancer in a non-oxidative chemotherapy scheme, with acceptable responses and no triggering hemolytic crisis." @default.
- W2955058547 created "2019-07-12" @default.
- W2955058547 creator A5006250695 @default.
- W2955058547 creator A5018074136 @default.
- W2955058547 creator A5022466989 @default.
- W2955058547 creator A5053397470 @default.
- W2955058547 creator A5058126569 @default.
- W2955058547 creator A5070887037 @default.
- W2955058547 date "2019-07-01" @default.
- W2955058547 modified "2023-10-14" @default.
- W2955058547 title "Safe neoadjuvant trastuzumab-based treatment in HER2 + inflammatory early breast cancer in a glucose 6-phosphate dehydrogenase-deficient postmenopausal woman: A case report and review of the literature" @default.
- W2955058547 cites W1974786987 @default.
- W2955058547 cites W1983705029 @default.
- W2955058547 cites W1987326983 @default.
- W2955058547 cites W1992989105 @default.
- W2955058547 cites W2005920747 @default.
- W2955058547 cites W2030456327 @default.
- W2955058547 cites W2091451530 @default.
- W2955058547 cites W2104272500 @default.
- W2955058547 cites W2105455287 @default.
- W2955058547 cites W2149908785 @default.
- W2955058547 cites W2153565541 @default.
- W2955058547 cites W2201278674 @default.
- W2955058547 doi "https://doi.org/10.1177/1078155219858173" @default.
- W2955058547 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31260379" @default.
- W2955058547 hasPublicationYear "2019" @default.
- W2955058547 type Work @default.
- W2955058547 sameAs 2955058547 @default.
- W2955058547 citedByCount "1" @default.
- W2955058547 countsByYear W29550585472020 @default.
- W2955058547 crossrefType "journal-article" @default.
- W2955058547 hasAuthorship W2955058547A5006250695 @default.
- W2955058547 hasAuthorship W2955058547A5018074136 @default.
- W2955058547 hasAuthorship W2955058547A5022466989 @default.
- W2955058547 hasAuthorship W2955058547A5053397470 @default.
- W2955058547 hasAuthorship W2955058547A5058126569 @default.
- W2955058547 hasAuthorship W2955058547A5070887037 @default.
- W2955058547 hasConcept C121608353 @default.
- W2955058547 hasConcept C126322002 @default.
- W2955058547 hasConcept C143998085 @default.
- W2955058547 hasConcept C2776694085 @default.
- W2955058547 hasConcept C2776802502 @default.
- W2955058547 hasConcept C2777863537 @default.
- W2955058547 hasConcept C2778119762 @default.
- W2955058547 hasConcept C2778239845 @default.
- W2955058547 hasConcept C2779786085 @default.
- W2955058547 hasConcept C2781190966 @default.
- W2955058547 hasConcept C2781451048 @default.
- W2955058547 hasConcept C530470458 @default.
- W2955058547 hasConcept C71924100 @default.
- W2955058547 hasConceptScore W2955058547C121608353 @default.
- W2955058547 hasConceptScore W2955058547C126322002 @default.
- W2955058547 hasConceptScore W2955058547C143998085 @default.
- W2955058547 hasConceptScore W2955058547C2776694085 @default.
- W2955058547 hasConceptScore W2955058547C2776802502 @default.
- W2955058547 hasConceptScore W2955058547C2777863537 @default.
- W2955058547 hasConceptScore W2955058547C2778119762 @default.
- W2955058547 hasConceptScore W2955058547C2778239845 @default.
- W2955058547 hasConceptScore W2955058547C2779786085 @default.
- W2955058547 hasConceptScore W2955058547C2781190966 @default.
- W2955058547 hasConceptScore W2955058547C2781451048 @default.
- W2955058547 hasConceptScore W2955058547C530470458 @default.
- W2955058547 hasConceptScore W2955058547C71924100 @default.
- W2955058547 hasLocation W29550585471 @default.
- W2955058547 hasLocation W29550585472 @default.
- W2955058547 hasOpenAccess W2955058547 @default.
- W2955058547 hasPrimaryLocation W29550585471 @default.
- W2955058547 hasRelatedWork W2004818507 @default.
- W2955058547 hasRelatedWork W2052405826 @default.
- W2955058547 hasRelatedWork W2144124503 @default.
- W2955058547 hasRelatedWork W2153331156 @default.
- W2955058547 hasRelatedWork W2352586227 @default.
- W2955058547 hasRelatedWork W2781041469 @default.
- W2955058547 hasRelatedWork W4232759728 @default.
- W2955058547 hasRelatedWork W4232824905 @default.
- W2955058547 hasRelatedWork W4255825072 @default.
- W2955058547 hasRelatedWork W4298186602 @default.
- W2955058547 isParatext "false" @default.
- W2955058547 isRetracted "false" @default.
- W2955058547 magId "2955058547" @default.
- W2955058547 workType "article" @default.