Matches in SemOpenAlex for { <https://semopenalex.org/work/W2955093604> ?p ?o ?g. }
- W2955093604 endingPage "4161" @default.
- W2955093604 startingPage "4147" @default.
- W2955093604 abstract "The dual (pH- and temperature-) responsive core-shell structured mesoporous nanomaterial [email protected] were prepared using bimodal mesoporous silica as a core and poly(N-isopropylacrylamide-co-acrylic acid) P(NIPAM-co-AA) copolymer as a shell. Ibuprofen (IBU) was used as a model drug, and the effects of copolymer-coated shell thickness on drug loading and controlled release behavior were investigated by means of N2 sorption isotherms, dynamic light scattering measurements, X-ray diffraction patterns, Fourier transform infrared spectra, scanning electron and transmission electron microscopy, thermogravimetric profiles, and elemental analysis techniques. Particularly, their fractal evolutions in the drug delivery durations were explored via small angle X-ray scattering methods, demonstrating that the resultant [email protected] before IBU-loading and after releasing possess the typical fractal features with spherical morphology. Meanwhile, the estimation for shell thickness of [email protected] coating in different time intervals indicated that the drug-loaded capacity was improved with the increasing shell thickness, but drug-released rate varies, strongly depending on both shell thickness and release conditions. The drug delivery mechanism was preliminarily explored, following the Korsmeyer-Peppas model. Finally, cytotoxicity in cell and pharmacokinetic of released-IBU from hybrid nanocomposite in mice via intravenously injection were preliminarily explored." @default.
- W2955093604 created "2019-07-12" @default.
- W2955093604 creator A5001493292 @default.
- W2955093604 creator A5017960750 @default.
- W2955093604 creator A5038328748 @default.
- W2955093604 creator A5059192794 @default.
- W2955093604 creator A5062524509 @default.
- W2955093604 creator A5082888540 @default.
- W2955093604 date "2020-02-01" @default.
- W2955093604 modified "2023-10-06" @default.
- W2955093604 title "Fractal evolution of dual pH- and temperature-responsive P(NIPAM-co-AA)@BMMs with bimodal mesoporous silica core and coated-copolymer shell during drug delivery procedure via SAXS characterization" @default.
- W2955093604 cites W1077569315 @default.
- W2955093604 cites W1795159563 @default.
- W2955093604 cites W1855590262 @default.
- W2955093604 cites W1971062640 @default.
- W2955093604 cites W1980338488 @default.
- W2955093604 cites W1983406611 @default.
- W2955093604 cites W1987814181 @default.
- W2955093604 cites W1991530095 @default.
- W2955093604 cites W1995830036 @default.
- W2955093604 cites W2001332989 @default.
- W2955093604 cites W2005790118 @default.
- W2955093604 cites W2005796211 @default.
- W2955093604 cites W2006643725 @default.
- W2955093604 cites W2008123727 @default.
- W2955093604 cites W2012732264 @default.
- W2955093604 cites W2025042193 @default.
- W2955093604 cites W2031414552 @default.
- W2955093604 cites W2034791599 @default.
- W2955093604 cites W2039280964 @default.
- W2955093604 cites W2041724513 @default.
- W2955093604 cites W2046151551 @default.
- W2955093604 cites W2047231904 @default.
- W2955093604 cites W2058293286 @default.
- W2955093604 cites W2060320802 @default.
- W2955093604 cites W2075343653 @default.
- W2955093604 cites W2078341385 @default.
- W2955093604 cites W2083735851 @default.
- W2955093604 cites W2085638225 @default.
- W2955093604 cites W2090003288 @default.
- W2955093604 cites W2094212341 @default.
- W2955093604 cites W2094234093 @default.
- W2955093604 cites W2094253502 @default.
- W2955093604 cites W2095407037 @default.
- W2955093604 cites W2098992799 @default.
- W2955093604 cites W2149183402 @default.
- W2955093604 cites W2163615705 @default.
- W2955093604 cites W2164289512 @default.
- W2955093604 cites W2167243784 @default.
- W2955093604 cites W2312310496 @default.
- W2955093604 cites W2315273606 @default.
- W2955093604 cites W2318923840 @default.
- W2955093604 cites W2319087339 @default.
- W2955093604 cites W2322997362 @default.
- W2955093604 cites W2323616505 @default.
- W2955093604 cites W2328156915 @default.
- W2955093604 cites W2329007701 @default.
- W2955093604 cites W2330636336 @default.
- W2955093604 cites W2345546670 @default.
- W2955093604 cites W2402964195 @default.
- W2955093604 cites W2409329045 @default.
- W2955093604 cites W2516665003 @default.
- W2955093604 cites W2527134266 @default.
- W2955093604 cites W2550223901 @default.
- W2955093604 cites W2555458625 @default.
- W2955093604 cites W2609845023 @default.
- W2955093604 cites W2611229562 @default.
- W2955093604 cites W2621108207 @default.
- W2955093604 cites W2763401070 @default.
- W2955093604 cites W2769298264 @default.
- W2955093604 cites W2781493475 @default.
- W2955093604 cites W2789247964 @default.
- W2955093604 cites W2790543096 @default.
- W2955093604 cites W2806208423 @default.
- W2955093604 cites W2907159201 @default.
- W2955093604 cites W2935810358 @default.
- W2955093604 cites W3047055559 @default.
- W2955093604 cites W346644260 @default.
- W2955093604 doi "https://doi.org/10.1016/j.arabjc.2019.06.012" @default.
- W2955093604 hasPublicationYear "2020" @default.
- W2955093604 type Work @default.
- W2955093604 sameAs 2955093604 @default.
- W2955093604 citedByCount "7" @default.
- W2955093604 countsByYear W29550936042020 @default.
- W2955093604 countsByYear W29550936042022 @default.
- W2955093604 countsByYear W29550936042023 @default.
- W2955093604 crossrefType "journal-article" @default.
- W2955093604 hasAuthorship W2955093604A5001493292 @default.
- W2955093604 hasAuthorship W2955093604A5017960750 @default.
- W2955093604 hasAuthorship W2955093604A5038328748 @default.
- W2955093604 hasAuthorship W2955093604A5059192794 @default.
- W2955093604 hasAuthorship W2955093604A5062524509 @default.
- W2955093604 hasAuthorship W2955093604A5082888540 @default.
- W2955093604 hasBestOaLocation W29550936041 @default.
- W2955093604 hasConcept C120665830 @default.
- W2955093604 hasConcept C121332964 @default.
- W2955093604 hasConcept C127413603 @default.
- W2955093604 hasConcept C131888329 @default.