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• W2955141207 abstract "Ascidians are marine animals that belong to the same phylogenetic group (Phylum Chordata) as human beings do. One of the three suborders in ascidians can accumulate a high level of vanadium ions in blood cells. Ascidia gemmata has been reported to accumulate the highest levels of vanadium at 350 mM, which is 107-fold higher than the vanadium concentration in seawater. In the last two decades, many genes and proteins related to vanadium accumulation and reduction have been revealed by molecular biological and biochemical methods. Modern omics approach enhanced the comprehensive identification of factors related to this phenomenon. In this review article, first, we would like to summarize the history of studies on vanadium accumulation in ascidians briefly. Then, we would like to overview recent advances by omics studies. How ascidians selectively accumulate vanadium is discussed from biochemical properties of proteins responsible for each step, and why ascidians accumulate vanadium is discussed in relation to the underwater adhesion.Ascidians are marine animals that belong to the same phylogenetic group (Phylum Chordata) as human beings do. One of the three suborders in ascidians can accumulate a high level of vanadium ions in blood cells. Ascidia gemmata has been reported to accumulate the highest levels of vanadium at 350 mM, which is 107-fold higher than the vanadium concentration in seawater. In the last two decades, many genes and proteins related to vanadium accumulation and reduction have been revealed by molecular biological and biochemical methods. Modern omics approach enhanced the comprehensive identification of factors related to this phenomenon. In this review article, first, we would like to summarize the history of studies on vanadium accumulation in ascidians briefly. Then, we would like to overview recent advances by omics studies. How ascidians selectively accumulate vanadium is discussed from biochemical properties of proteins responsible for each step, and why ascidians accumulate vanadium is discussed in relation..." @default.
• W2955141207 created "2019-07-12" @default.
• W2955141207 creator A5008851124 @default.
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• W2955141207 date "2019-01-01" @default.
• W2955141207 modified "2023-09-25" @default.
• W2955141207 title "Mechanism of vanadium accumulation and possible function of vanadium in underwater adhesion in ascidians" @default.
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• W2955141207 doi "https://doi.org/10.1063/1.5115602" @default.
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