FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2955323250> ?p ?o ?g. }

• W2955323250 endingPage "112058" @default.
• W2955323250 startingPage "112058" @default.
• W2955323250 abstract "Angelica keiskei contains many bioactive components with anti-oxidative and anti-inflammatory effects. It is also effective for the treatment of diabetes mellitus, hypertension, and arteriosclerosis, but the relationships between these effects and the active components in the herb have not been studied.We aimed to confirm the effects of Angelica keiskei on humans.A metabolomics and lipidomics study was performed using human plasma samples from 20 subjects after the intake of Angelica keiskei, and the components of Angelica keiskei in the plasma were profiled. UPLC-Orbitrap-MS was used to analyze the plasma and plant extracts, and multivariate analysis and correlation studies between the exogenous components from plant and endogenous metabolite in plasma were performed.The levels of the 14 metabolites including kynurenic acid, prostaglandin E1, chenodeoxycholic acid, lysoPC (18:1), lysoPC (18:2), lysoPC (20:3), lysoPC (20:4), lysoPC (22:6), PC (34:1), PC (34:2), PC (38:3), PC (38:4), PC (38:6) and PC (40:7) in the plasma were changed. By monitoring the components originating from Angelica keiskei in plasma, five components including 5-methoxypsoralen, 8-methoxypsoralen, 4-hydroxyderricin, xanthoangelol B and xanthoangelol F were detected and they reduced the levels of bile acids and fatty acids.The levels of the metabolites, including bile acids, amino acids, glycerophospholipids and fatty acids, in the plasma were changed, and 14 significantly changed metabolites were closely related to the preventive effect against liver diseases, type 2 diabetes, anemia, obesity, atherosclerosis, depression and anti-inflammatory effects. The five components of Angelica keiskei were related the modulatory activity of reducing the levels of bile acids and fatty acids." @default.
• W2955323250 created "2019-07-12" @default.
• W2955323250 creator A5015230939 @default.
• W2955323250 creator A5023577608 @default.
• W2955323250 creator A5024501365 @default.
• W2955323250 creator A5042364551 @default.
• W2955323250 creator A5045361830 @default.
• W2955323250 creator A5055955541 @default.
• W2955323250 creator A5071192702 @default.
• W2955323250 creator A5075137190 @default.
• W2955323250 date "2019-10-01" @default.
• W2955323250 modified "2023-09-26" @default.
• W2955323250 title "Analysis of plasma metabolic profiling and evaluation of the effect of the intake of Angelica keiskei using metabolomics and lipidomics" @default.
• W2955323250 cites W1729384866 @default.
• W2955323250 cites W1975783279 @default.
• W2955323250 cites W1976566839 @default.
• W2955323250 cites W1977549848 @default.
• W2955323250 cites W1979202709 @default.
• W2955323250 cites W1987567635 @default.
• W2955323250 cites W1988088217 @default.
• W2955323250 cites W1992969398 @default.
• W2955323250 cites W2008930714 @default.
• W2955323250 cites W2017747698 @default.
• W2955323250 cites W2041548879 @default.
• W2955323250 cites W2043206071 @default.
• W2955323250 cites W2058843220 @default.
• W2955323250 cites W2069632591 @default.
• W2955323250 cites W2074310845 @default.
• W2955323250 cites W2077434210 @default.
• W2955323250 cites W2108904338 @default.
• W2955323250 cites W2128676795 @default.
• W2955323250 cites W2137558403 @default.
• W2955323250 cites W2139478702 @default.
• W2955323250 cites W2150764769 @default.
• W2955323250 cites W2414986683 @default.
• W2955323250 cites W2471009944 @default.
• W2955323250 cites W2519337429 @default.
• W2955323250 cites W2593436144 @default.
• W2955323250 cites W2709145818 @default.
• W2955323250 cites W2732932784 @default.
• W2955323250 cites W2783132192 @default.
• W2955323250 cites W2893865288 @default.
• W2955323250 cites W1870414600 @default.
• W2955323250 doi "https://doi.org/10.1016/j.jep.2019.112058" @default.
• W2955323250 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31283957" @default.
• W2955323250 hasPublicationYear "2019" @default.
• W2955323250 type Work @default.
• W2955323250 sameAs 2955323250 @default.
• W2955323250 citedByCount "13" @default.
• W2955323250 countsByYear W29553232502019 @default.
• W2955323250 countsByYear W29553232502020 @default.
• W2955323250 countsByYear W29553232502021 @default.
• W2955323250 countsByYear W29553232502022 @default.
• W2955323250 countsByYear W29553232502023 @default.
• W2955323250 crossrefType "journal-article" @default.
• W2955323250 hasAuthorship W2955323250A5015230939 @default.
• W2955323250 hasAuthorship W2955323250A5023577608 @default.
• W2955323250 hasAuthorship W2955323250A5024501365 @default.
• W2955323250 hasAuthorship W2955323250A5042364551 @default.
• W2955323250 hasAuthorship W2955323250A5045361830 @default.
• W2955323250 hasAuthorship W2955323250A5055955541 @default.
• W2955323250 hasAuthorship W2955323250A5071192702 @default.
• W2955323250 hasAuthorship W2955323250A5075137190 @default.
• W2955323250 hasConcept C185592680 @default.
• W2955323250 hasConcept C21565614 @default.
• W2955323250 hasConcept C2776706248 @default.
• W2955323250 hasConcept C2776841986 @default.
• W2955323250 hasConcept C43617362 @default.
• W2955323250 hasConcept C515207424 @default.
• W2955323250 hasConcept C55493867 @default.
• W2955323250 hasConcept C556039675 @default.
• W2955323250 hasConcept C58017582 @default.
• W2955323250 hasConcept C71924100 @default.
• W2955323250 hasConcept C98274493 @default.
• W2955323250 hasConceptScore W2955323250C185592680 @default.
• W2955323250 hasConceptScore W2955323250C21565614 @default.
• W2955323250 hasConceptScore W2955323250C2776706248 @default.
• W2955323250 hasConceptScore W2955323250C2776841986 @default.
• W2955323250 hasConceptScore W2955323250C43617362 @default.
• W2955323250 hasConceptScore W2955323250C515207424 @default.
• W2955323250 hasConceptScore W2955323250C55493867 @default.
• W2955323250 hasConceptScore W2955323250C556039675 @default.
• W2955323250 hasConceptScore W2955323250C58017582 @default.
• W2955323250 hasConceptScore W2955323250C71924100 @default.
• W2955323250 hasConceptScore W2955323250C98274493 @default.
• W2955323250 hasFunder F4320320671 @default.
• W2955323250 hasLocation W29553232501 @default.
• W2955323250 hasLocation W29553232502 @default.
• W2955323250 hasOpenAccess W2955323250 @default.
• W2955323250 hasPrimaryLocation W29553232501 @default.
• W2955323250 hasRelatedWork W2005071799 @default.
• W2955323250 hasRelatedWork W2465541034 @default.
• W2955323250 hasRelatedWork W2599879433 @default.
• W2955323250 hasRelatedWork W2767333346 @default.
• W2955323250 hasRelatedWork W2767360236 @default.
• W2955323250 hasRelatedWork W2791890312 @default.
• W2955323250 hasRelatedWork W2883822848 @default.
• W2955323250 hasRelatedWork W3025473344 @default.

• next