FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2955361781> ?p ?o ?g. }

• W2955361781 endingPage "e16148" @default.
• W2955361781 startingPage "e16148" @default.
• W2955361781 abstract "Abstract Non-functioning pituitary adenomas (NFPAs) are the most common pituitary tumors, and some exhibit locally invasive or even clinically aggressive behavior. Circular RNAs (circRNAs) are a reinvented class of non-coding RNAs that play important roles in tumor initiation and progression. CircRNA microarray assays were performed in 4 invasive and 4 non-invasive NFPAs, and 4 typically differential expression circRNAs were selected for validation using quantitative reverse transcription-polymerase chain reaction. The diagnostic and prognostic values of tested cirRNAs were further evaluated. Bioinformatics analysis and a literature review of potential miRNAs targets involved in pituitary tumor invasion were performed. A specific circRNA expression profile was detected between invasive and non-invasive NFPAs, including 91 upregulated and 61 downregulated circRNAs in invasive tumors. The dysregulation of the 4 circRNAs has been confirmed. The expression of hsa_circRNA_102597, a downregulated circRNA, was significantly correlated with tumor diameter ( P < .05) and Knosp grade ( P < .01). Hsa_circRNA_102597 alone or in combined with Ki-67 index was able to accurately differentiate invasive from non-invasive NFPAs as well as predict tumor progression/recurrence. Fourteen aberrantly expressed circRNAs might be involved in the invasiveness of pituitary adenomas via seven predicted potential miRNA targets. CircRNAs are participated in pituitary tumor invasion, and may be used as novel diagnostic and prognostic biomarkers in NFPAs." @default.
• W2955361781 created "2019-07-12" @default.
• W2955361781 creator A5009424735 @default.
• W2955361781 creator A5035286587 @default.
• W2955361781 creator A5036111618 @default.
• W2955361781 creator A5042523063 @default.
• W2955361781 creator A5045687280 @default.
• W2955361781 creator A5050266837 @default.
• W2955361781 creator A5050572872 @default.
• W2955361781 creator A5055814657 @default.
• W2955361781 creator A5070158282 @default.
• W2955361781 creator A5075403741 @default.
• W2955361781 creator A5084956602 @default.
• W2955361781 date "2019-06-01" @default.
• W2955361781 modified "2023-10-15" @default.
• W2955361781 title "Differential circular RNA expression profiles of invasive and non-invasive non-functioning pituitary adenomas" @default.
• W2955361781 cites W1866220599 @default.
• W2955361781 cites W1874402154 @default.
• W2955361781 cites W1963539523 @default.
• W2955361781 cites W1967695487 @default.
• W2955361781 cites W1971420336 @default.
• W2955361781 cites W2026921924 @default.
• W2955361781 cites W2030170263 @default.
• W2955361781 cites W2037170170 @default.
• W2955361781 cites W2047245583 @default.
• W2955361781 cites W2051091626 @default.
• W2955361781 cites W2052506678 @default.
• W2955361781 cites W2058835062 @default.
• W2955361781 cites W2064165694 @default.
• W2955361781 cites W2076285703 @default.
• W2955361781 cites W2088128227 @default.
• W2955361781 cites W2124405213 @default.
• W2955361781 cites W2132304416 @default.
• W2955361781 cites W2169967426 @default.
• W2955361781 cites W2284415752 @default.
• W2955361781 cites W2316171452 @default.
• W2955361781 cites W2395582734 @default.
• W2955361781 cites W2398883032 @default.
• W2955361781 cites W2410272781 @default.
• W2955361781 cites W2476707374 @default.
• W2955361781 cites W2509105303 @default.
• W2955361781 cites W2514180887 @default.
• W2955361781 cites W2517463990 @default.
• W2955361781 cites W2560091712 @default.
• W2955361781 cites W2579878967 @default.
• W2955361781 cites W2582820149 @default.
• W2955361781 cites W2586427318 @default.
• W2955361781 cites W2588123797 @default.
• W2955361781 cites W2593315117 @default.
• W2955361781 cites W2596640287 @default.
• W2955361781 cites W2597380512 @default.
• W2955361781 cites W2758199888 @default.
• W2955361781 doi "https://doi.org/10.1097/md.0000000000016148" @default.
• W2955361781 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6616958" @default.
• W2955361781 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31261542" @default.
• W2955361781 hasPublicationYear "2019" @default.
• W2955361781 type Work @default.
• W2955361781 sameAs 2955361781 @default.
• W2955361781 citedByCount "9" @default.
• W2955361781 countsByYear W29553617812020 @default.
• W2955361781 countsByYear W29553617812021 @default.
• W2955361781 countsByYear W29553617812022 @default.
• W2955361781 countsByYear W29553617812023 @default.
• W2955361781 crossrefType "journal-article" @default.
• W2955361781 hasAuthorship W2955361781A5009424735 @default.
• W2955361781 hasAuthorship W2955361781A5035286587 @default.
• W2955361781 hasAuthorship W2955361781A5036111618 @default.
• W2955361781 hasAuthorship W2955361781A5042523063 @default.
• W2955361781 hasAuthorship W2955361781A5045687280 @default.
• W2955361781 hasAuthorship W2955361781A5050266837 @default.
• W2955361781 hasAuthorship W2955361781A5050572872 @default.
• W2955361781 hasAuthorship W2955361781A5055814657 @default.
• W2955361781 hasAuthorship W2955361781A5070158282 @default.
• W2955361781 hasAuthorship W2955361781A5075403741 @default.
• W2955361781 hasAuthorship W2955361781A5084956602 @default.
• W2955361781 hasBestOaLocation W29553617811 @default.
• W2955361781 hasConcept C104317684 @default.
• W2955361781 hasConcept C121608353 @default.
• W2955361781 hasConcept C126322002 @default.
• W2955361781 hasConcept C127561419 @default.
• W2955361781 hasConcept C142724271 @default.
• W2955361781 hasConcept C145059251 @default.
• W2955361781 hasConcept C150194340 @default.
• W2955361781 hasConcept C186836561 @default.
• W2955361781 hasConcept C2775893923 @default.
• W2955361781 hasConcept C2779256057 @default.
• W2955361781 hasConcept C2780801072 @default.
• W2955361781 hasConcept C2781449511 @default.
• W2955361781 hasConcept C502942594 @default.
• W2955361781 hasConcept C54355233 @default.
• W2955361781 hasConcept C71924100 @default.
• W2955361781 hasConcept C8415881 @default.
• W2955361781 hasConcept C86803240 @default.
• W2955361781 hasConceptScore W2955361781C104317684 @default.
• W2955361781 hasConceptScore W2955361781C121608353 @default.
• W2955361781 hasConceptScore W2955361781C126322002 @default.
• W2955361781 hasConceptScore W2955361781C127561419 @default.
• W2955361781 hasConceptScore W2955361781C142724271 @default.

• next