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• W2955366557 endingPage "109948" @default.
• W2955366557 startingPage "109948" @default.
• W2955366557 abstract "Macrophages play an important role in foreign body reaction (FBR), and exhibit a detrimental or beneficial function in tissue repair while polarized into different phenotypes. The objective of this work is to evaluate the effect of three-dimensional (3D) porous polyetheretherketone (PEEK) on macrophage polarization through sulfonating PEEK and establishing a mouse air pouch model. The in vivo results show that the sulfonated PEEK induced higher levels of anti-inflammatory cytokine together with lower levels of pro-inflammatory cytokine. In addition, it was found that a relatively mild infiltration of inflammatory cells was caused and there were more M2 macrophages and less M1 ones when compared with PEEK. It indicates that 3D porous PEEK induces a shift to M2 macrophages and has large potential in regenerative medicine application." @default.
• W2955366557 created "2019-07-12" @default.
• W2955366557 creator A5036891682 @default.
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• W2955366557 date "2019-11-01" @default.
• W2955366557 modified "2023-10-16" @default.
• W2955366557 title "Macrophage polarization following three-dimensional porous PEEK" @default.
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• W2955366557 doi "https://doi.org/10.1016/j.msec.2019.109948" @default.
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• W2955366557 hasPublicationYear "2019" @default.
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