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• W2955371978 endingPage "109941" @default.
• W2955371978 startingPage "109941" @default.
• W2955371978 abstract "In 2014-2015, 61,421 total knee arthroplasties (TKAs) were performed in Canada; an increase of about 20% over 2000-2001. Revision total knee arthroplasties (rTKAs) accounted for 6.8% of TKAs performed between 2014 and 2015, and this is estimated to grow another 12% by 2025. rTKAs are typically more complicated than primary TKAs due to the significant loss of femoral and tibial bone stock. The escalating demand and limitations associated with total knee arthroplasty and their revision drives the development of novel treatments. A variety of materials have been utilized to facilitate regeneration of healthy bone around the site of a knee arthroplasty. The selection of these materials is based on the bone defect size and includes bone grafts, graft substitutes and cements. However, all these materials have certain disadvantages such as blood loss, disease transmission (bone grafts), inflammatory response, insufficient mechanical properties (bone graft substitutes) thermal necrosis and stress shielding (bone cement). Recently, the use of metal augments for large bone defects has attracted attention, however they can undergo fretting, corrosion, and stress shielding. All things considered, this review indicates the necessity of developing augments that have structural integrities and biodegradation rates similar to that of human bone. Therefore, the future of bone loss management may lie in fabricating novel bioactive glass augments as they can promote bone healing and implant stability and can degrade with time." @default.
• W2955371978 created "2019-07-12" @default.
• W2955371978 creator A5041062242 @default.
• W2955371978 creator A5044118850 @default.
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• W2955371978 creator A5074049796 @default.
• W2955371978 creator A5076506741 @default.
• W2955371978 creator A5086444103 @default.
• W2955371978 date "2019-11-01" @default.
• W2955371978 modified "2023-10-05" @default.
• W2955371978 title "A review of materials for managing bone loss in revision total knee arthroplasty" @default.
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