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- W2955406583 abstract "Near-infrared spectroscopy (NIRS) is used to investigate muscle oxygenation, but the association of muscle deoxygenation (deoxygenated hemoglobin, deoxy[Hb+Mb]; ΔHHb) to workload during exercise needs further study. PURPOSE: To characterize the relationship between the change in muscle deoxygenation (ΔHHb) and maximal workload (MW) achieved during maximal cardiopulmonary exercise test (CPET). METHODS: 6 men and 5 women (mean + SD: 39.09 ± 17.2 years [age]) underwent CPET on a recumbent cycle ergometer. ΔHHb in the vastus lateralis muscle was measured using NIRS, and MW as recorded in Watts. A polynomial model (ΔHHb ~ MW + MW^2 + peak oxygen uptake; VO2peak) was compared to a semi-linear regression model (with an added interaction term between VO2peak and MW) to characterize the relationship. RESULTS: ΔHHb during CPET was strongly correlated with peak workload (0.881, p=0.0003) and VO2peak (0.934, p=0.0001). The polynomial model explaining the relationship was significant (Adj.R2:0.821, F(4,7)= 7.853, p=0.009); however, the point estimates were not . The semi-linear regression model was better able to characterize the overall trend (Adj.R2: 0.90, p=0.0002) and the drop in ΔHHb at the higher ends of MW, and indicated that VO2peak had a significant effect (B=54.9, p=0.019), and interacted with MW (B=-0.157, p=0.04). CONCLUSION: These preliminary results show that the linear increase in ΔHHb with incremental workload appears to attenuate and slightly decrease at greater MW, especially for those with higher exercise capacity. Supported by NIH Grant K01HD084690-01A1." @default.
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- W2955406583 date "2019-06-01" @default.
- W2955406583 modified "2023-10-03" @default.
- W2955406583 title "Relationship Between Muscle Deoxygenation And Workload At Peak Exercise In Healthy Adults Using Near-infrared Spectroscopy" @default.
- W2955406583 doi "https://doi.org/10.1249/01.mss.0000561407.14368.e4" @default.
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