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- W2955542935 endingPage "114" @default.
- W2955542935 startingPage "97" @default.
- W2955542935 abstract "Nanocarriers (NCs) are a type of drug delivery system commonly used to regulate the pharmacokinetic and pharmacodynamic properties of drugs. Although a wide variety of NCs has been developed, relatively few have been registered for clinical trials and even fewer are clinically approved. Overt or potential toxicity, indistinct mechanisms of drug release and unsatisfactory pharmacokinetic behavior all contribute to their high failure rate during preclinical and clinical testing. These negative characteristics are not only due to the NCs themselves but also to the materials of the drug nanocarrier system (MDNS) that are released in vivo. In this article, we review the main analytical techniques used for bioassay of NCs and MDNS and their pharmacokinetics after administration by various routes. We anticipate our review will serve to improve the understanding of MDNS pharmacokinetics and facilitate the development of NC drug delivery systems." @default.
- W2955542935 created "2019-07-12" @default.
- W2955542935 creator A5005818424 @default.
- W2955542935 creator A5030428842 @default.
- W2955542935 creator A5034927324 @default.
- W2955542935 creator A5038556283 @default.
- W2955542935 creator A5051178495 @default.
- W2955542935 creator A5063035403 @default.
- W2955542935 date "2019-03-01" @default.
- W2955542935 modified "2023-10-16" @default.
- W2955542935 title "Absorption, distribution, metabolism and excretion of the biomaterials used in Nanocarrier drug delivery systems" @default.
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