FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2955642130> ?p ?o ?g. }

• W2955642130 endingPage "1864" @default.
• W2955642130 startingPage "1859" @default.
• W2955642130 abstract "To investigate complement activation in aqueous humour of patients with early, intermediate and neovascular age-related macular degeneration (AMD). Aqueous humour of 79 AMD patients (early, intermediate and neovascular) and 77 age-matched controls was prospectively collected. The levels of the complement protein 3 (C3), activation products complement factor 3a (C3a) and Ba, C3b/iC3b, complement factors B, H and I (CFB, CFH and CFI), and total protein concentration were measured. Data were modelled using covariate analysis to assess the impact of age and glaucoma status of patients and total protein concentration of samples on complement protein concentration across groups. C3a concentration was significantly increased in the aqueous humour of early (p = 0.016), intermediate (p = 0.003) and neovascular (p = 0.018) AMD patients, whilst C3 concentration was significantly increased in early AMD patients only (p = 0.019). Levels of CFB and CFH were significantly increased in the aqueous humour of neovascular AMD patients (p = 0.023 and p = 0.018, respectively). Our findings provide evidence for early local complement dysregulation in AMD patients, suggesting that complement pathway inhibition may be a clinically relevant intervention for early stages of AMD." @default.
• W2955642130 created "2019-07-12" @default.
• W2955642130 creator A5010104554 @default.
• W2955642130 creator A5010165139 @default.
• W2955642130 creator A5019858692 @default.
• W2955642130 creator A5034780611 @default.
• W2955642130 creator A5072723519 @default.
• W2955642130 creator A5074938732 @default.
• W2955642130 creator A5077993009 @default.
• W2955642130 creator A5085898146 @default.
• W2955642130 creator A5090453978 @default.
• W2955642130 date "2019-07-02" @default.
• W2955642130 modified "2023-10-18" @default.
• W2955642130 title "Early local activation of complement in aqueous humour of patients with age-related macular degeneration" @default.
• W2955642130 cites W121889566 @default.
• W2955642130 cites W1486365785 @default.
• W2955642130 cites W1511644085 @default.
• W2955642130 cites W1760485743 @default.
• W2955642130 cites W1853339213 @default.
• W2955642130 cites W1977327764 @default.
• W2955642130 cites W1989747234 @default.
• W2955642130 cites W2027707278 @default.
• W2955642130 cites W2044712549 @default.
• W2955642130 cites W2060767100 @default.
• W2955642130 cites W2070576387 @default.
• W2955642130 cites W2096618178 @default.
• W2955642130 cites W2117386992 @default.
• W2955642130 cites W2134537124 @default.
• W2955642130 cites W2136501493 @default.
• W2955642130 cites W2141588316 @default.
• W2955642130 cites W2169333648 @default.
• W2955642130 cites W2233221674 @default.
• W2955642130 cites W2582581571 @default.
• W2955642130 cites W2754409727 @default.
• W2955642130 cites W2770722600 @default.
• W2955642130 cites W2809531722 @default.
• W2955642130 cites W2949774640 @default.
• W2955642130 cites W4300819821 @default.
• W2955642130 doi "https://doi.org/10.1038/s41433-019-0501-4" @default.
• W2955642130 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7002716" @default.
• W2955642130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31267090" @default.
• W2955642130 hasPublicationYear "2019" @default.
• W2955642130 type Work @default.
• W2955642130 sameAs 2955642130 @default.
• W2955642130 citedByCount "20" @default.
• W2955642130 countsByYear W29556421302020 @default.
• W2955642130 countsByYear W29556421302021 @default.
• W2955642130 countsByYear W29556421302022 @default.
• W2955642130 countsByYear W29556421302023 @default.
• W2955642130 crossrefType "journal-article" @default.
• W2955642130 hasAuthorship W2955642130A5010104554 @default.
• W2955642130 hasAuthorship W2955642130A5010165139 @default.
• W2955642130 hasAuthorship W2955642130A5019858692 @default.
• W2955642130 hasAuthorship W2955642130A5034780611 @default.
• W2955642130 hasAuthorship W2955642130A5072723519 @default.
• W2955642130 hasAuthorship W2955642130A5074938732 @default.
• W2955642130 hasAuthorship W2955642130A5077993009 @default.
• W2955642130 hasAuthorship W2955642130A5085898146 @default.
• W2955642130 hasAuthorship W2955642130A5090453978 @default.
• W2955642130 hasBestOaLocation W29556421301 @default.
• W2955642130 hasConcept C104317684 @default.
• W2955642130 hasConcept C111684460 @default.
• W2955642130 hasConcept C112313634 @default.
• W2955642130 hasConcept C118487528 @default.
• W2955642130 hasConcept C127716648 @default.
• W2955642130 hasConcept C14356644 @default.
• W2955642130 hasConcept C159654299 @default.
• W2955642130 hasConcept C179369057 @default.
• W2955642130 hasConcept C185592680 @default.
• W2955642130 hasConcept C188082640 @default.
• W2955642130 hasConcept C191590540 @default.
• W2955642130 hasConcept C203014093 @default.
• W2955642130 hasConcept C2776403814 @default.
• W2955642130 hasConcept C2779984381 @default.
• W2955642130 hasConcept C2781359195 @default.
• W2955642130 hasConcept C2993390227 @default.
• W2955642130 hasConcept C55493867 @default.
• W2955642130 hasConcept C71924100 @default.
• W2955642130 hasConceptScore W2955642130C104317684 @default.
• W2955642130 hasConceptScore W2955642130C111684460 @default.
• W2955642130 hasConceptScore W2955642130C112313634 @default.
• W2955642130 hasConceptScore W2955642130C118487528 @default.
• W2955642130 hasConceptScore W2955642130C127716648 @default.
• W2955642130 hasConceptScore W2955642130C14356644 @default.
• W2955642130 hasConceptScore W2955642130C159654299 @default.
• W2955642130 hasConceptScore W2955642130C179369057 @default.
• W2955642130 hasConceptScore W2955642130C185592680 @default.
• W2955642130 hasConceptScore W2955642130C188082640 @default.
• W2955642130 hasConceptScore W2955642130C191590540 @default.
• W2955642130 hasConceptScore W2955642130C203014093 @default.
• W2955642130 hasConceptScore W2955642130C2776403814 @default.
• W2955642130 hasConceptScore W2955642130C2779984381 @default.
• W2955642130 hasConceptScore W2955642130C2781359195 @default.
• W2955642130 hasConceptScore W2955642130C2993390227 @default.
• W2955642130 hasConceptScore W2955642130C55493867 @default.
• W2955642130 hasConceptScore W2955642130C71924100 @default.
• W2955642130 hasFunder F4320307779 @default.
• W2955642130 hasIssue "12" @default.

• next