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• W2955644788 abstract "Cerebral Palsy (CP) is a neurological disorder caused by lesions in the brain and is characterized by impaired motor function, musculoskeletal deformity, and atrophy. Individuals with CP appear to develop osteoporosis at an earlier age compared to general population. Bone weakness has adverse effects on the muscular system, which causes CP population to be more prone to fractures and further immobility. Bone mineral density (BMD) improves in the general population via resistance training. However, it is still uncertain whether resistance training alters skeletal strength in the CP population and whether it influences musculoskeletal architecture and strength. PURPOSE: To determine the effect of resistance training on BMD, skeletal architecture, and muscular strength in adults with CP. METHODS: We studied 14 adults with and without CP. CP participants went through 3 months of resistance training twice per week. Dual-energy X-ray absorptiometry was used to measure local BMD at the lumbar spine (L1-L4), proximal femur, and radial/ulnar regions. Architectural differences were identified by measuring various angles and lengths on the proximal femur. Leg muscular strength was measured during knee extension and flexion using the Humac Norm Isokinetic Dynamometer. RESULTS: There was a significant increase in BMD at femur in CP group after 3 month exercise (0.6±0.1 CPpre vs. 0.9±0.1 CPpost g/cm2; P<0.05). BMD at lumbar and forearm regions in CP group was similar to control group even though BMD in CP group seemed to improve after training (P>0.05). Skeletal architecture and muscular strength were significantly lower in CP compared to control, but it did not change after resistance training (architectural angle; 64±5 CPpre vs. 70±2 CPpost degree; P>0.05). While control group showed a strong linear relationship between femoral neck BMD and knee extensor peak torque (R2=0.83), CPpre showed no relationship (R2=0.01). After 3 months of training, CP participants who exhibited higher BMD appeared to develop greater muscular strength (R2=0.26). CONCLUSION: These findings suggest that short term resistance training improved skeletal strength in CP adults without alterations in skeletal architecture. Skeletal strength appeared to play a role in enhanced muscular strength in adults with CP only after exercise training." @default.
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• W2955644788 date "2019-06-01" @default.
• W2955644788 modified "2023-09-27" @default.
• W2955644788 title "Differential Effect of Resistance Training on Musculoskeletal Architecture and Strength in Adults with Cerebral Palsy" @default.
• W2955644788 doi "https://doi.org/10.1249/01.mss.0000563147.73731.c6" @default.
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