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• W2955687400 abstract "PURPOSE: The aim of this study was to verify if creatine supplementation in conjunction with a community-based exercise program improved cognition in elderly women. METHODS: Twenty elderly women were randomized into 2 groups: creatine (CRE, n=10, age = 71± 6 y; body mass = 67.4± 6.0 kg; height = 166±2 cm) or control (CON, n=10, age = 73±6 y; body mass = 67.4±5.7 kg; height = 164±4 cm). All subjects were active and did not use CM or pro-cognitive drugs before the experiment. CRE group received 2.0 g.kg body mass-1·d-1 of CM for 28 days. CON group received 2,0 g.kg body mass-1.day-1 of dextrosol. Community-based exercises (walking, dancing, calisthenics, stretching) were performed 3x a week with 1 h per session. Cognition was assessed using a battery of five tests: a Visual Reaction Time (VRT) test, a visual GO/NO GO reaction time (GNG) test; a Differentiation task test (DTT), an Eriksen flanker test (EFT), and a Corsi block test (CBT). Subjects completed a familiarization, taking the testing battery on two sessions over nonconsecutive days the week prior to the experiment. The week after familiarization, subjects completed the test battery and initiated supplementation (CRE or CON). After 28 days, they repeated the test battery. Chi-square tests were used to compare groups and sessions for DTT, EFT, and CBT. Repeated measures ANOVA were used to compare VRT and GNG. Significance level was set p≤ 0.05. RESULTS: Significant (p≤ 0.05) pre-post performance increases in GNG, EFT, and CBT were observed in CRE vs. CON (table 1). We did not find difference between moments or groups in VRT (p>0.05) nor DTT (p>0.05). Table 1 - Cognitive tests results *p ≤0.05 difference from other means according to ANOVA. Differing superscripts (a,b) indicate p ≤ 0.05 difference according to Chi-SquareTable 1: Cognitive tests results *p ≤0.05 difference from other means according to ANOVA. Differing superscripts (a,b) indicate p ≤ 0.05 difference according to Chi-SquareCONCLUSIONS: We conclude that 2g·kg-1·day-1 during 28 days of oral CM supplementation improved results in some cognitions tasks in elderly woman." @default.
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• W2955687400 date "2019-06-01" @default.
• W2955687400 modified "2023-09-27" @default.
• W2955687400 title "Oral Creatine Supplementation On Physicaly Active Elderly Women Cognition Improvement" @default.
• W2955687400 doi "https://doi.org/10.1249/01.mss.0000560749.36066.0f" @default.
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