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• W2955687533 startingPage "175628641985972" @default.
• W2955687533 abstract "Brain imaging is increasingly used to support clinicians in diagnosing multiple sclerosis (MS) and monitoring its progression. However, the role of magnetic resonance imaging (MRI) in MS goes far beyond its clinical application. Indeed, advanced imaging techniques have helped to detect different components of MS pathogenesis in vivo, which is now considered a heterogeneous process characterized by widespread damage of the central nervous system, rather than multifocal demyelination of white matter. Recently, MRI biomarkers more sensitive to disease activity than clinical disability outcome measures, have been used to monitor response to anti-inflammatory agents in patients with relapsing–remitting MS. Similarly, MRI markers of neurodegeneration exhibit the potential as primary and secondary outcomes in clinical trials for progressive phenotypes. This review will summarize recent advances in brain neuroimaging in MS from the research setting to clinical applications." @default.
• W2955687533 created "2019-07-12" @default.
• W2955687533 creator A5009133924 @default.
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• W2955687533 creator A5050596128 @default.
• W2955687533 creator A5067383775 @default.
• W2955687533 date "2019-01-01" @default.
• W2955687533 modified "2023-09-25" @default.
• W2955687533 title "Advances in brain imaging in multiple sclerosis" @default.
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