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• W2955721310 abstract "Changes in astrocyte channels, transporters, and metabolism play a critical role in seizure generation and epilepsy. In particular, alterations in astrocyte potassium, glutamate, water and adenosine homeostasis and gap junctional coupling have all been associated with hyperexcitability and epileptogenesis (largely in temporal lobe epilepsy). Distinct astrocytic changes have also been identified in other types of epilepsy, such as tuberous sclerosis, tumor-associated epilepsy and post-traumatic epilepsy. Together, the emerging literature on astrocytes and epilepsy provides powerful rationale for distinct new therapeutic targets that are astrocyte-specific." @default.
• W2955721310 created "2019-07-12" @default.
• W2955721310 creator A5012744570 @default.
• W2955721310 creator A5044077667 @default.
• W2955721310 date "2016-01-01" @default.
• W2955721310 modified "2023-10-18" @default.
• W2955721310 title "Astrocytes and Epilepsy" @default.
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