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• W2955864087 endingPage "296" @default.
• W2955864087 startingPage "282" @default.
• W2955864087 abstract "Psychologists usually perform a preliminary assessment of the person's cognitive status through a brief interview conducted before the formal testing. However, this exam has not yet been standardized with ad hoc recommendations in psychology literature. In this work, a standard observational NeuroPsychological Examination (NPE) designed for psychologists was proposed, and its clinical effectiveness evaluated. The NPE was administered to patients referred to a neuropsychological service in a memory clinic over a 2-year period. The NPEs of the patients with Alzheimer dementia (AD), vascular dementia (VaD), and healthy controls (HC) were retrospectively retrieved. Comparisons among the three groups were conducted. Abnormalities/signs identified during the NPE in the AD and VaD groups are more numerous compared to those reported in the HC group. About 80% of HCs show none or only one abnormal sign. Vice versa, 87.5% of both AD and VaD patients show three or more abnormalities. Accordingly, the NPE has 0.88 (95%CI = 0.81-0.95) sensitivity and 0.95 (95%CI = 0.88-1.02) specificity for detecting cognitive decline when a cut-point of three or more signs is applied. Some significant differences also emerge on the number of pathological signs between AD and VaD patients. NPE is a promising tool with demonstrated diagnostic utility in dementia patients." @default.
• W2955864087 created "2019-07-12" @default.
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• W2955864087 date "2019-07-03" @default.
• W2955864087 modified "2023-09-27" @default.
• W2955864087 title "Signs and symptoms method in neuropsychology: A preliminary investigation of a standardized clinical interview for assessment of cognitive decline in dementia" @default.
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• W2955864087 doi "https://doi.org/10.1080/23279095.2019.1630626" @default.
• W2955864087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31269816" @default.
• W2955864087 hasPublicationYear "2019" @default.
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