Matches in SemOpenAlex for { <https://semopenalex.org/work/W2955897025> ?p ?o ?g. }
- W2955897025 endingPage "13" @default.
- W2955897025 startingPage "1" @default.
- W2955897025 abstract "The therapeutic effects of telmisartan, an angiotensin II receptor antagonist and a peroxisome proliferator-activated receptor- γ (PPAR- γ ) agonist, have been demonstrated in several disorders. It has antioxidant and immune response modulator properties and has shown promising results in the treatment of an ischemia/reperfusion (I/R) lesion. In this study, a skeletal muscle (right gastrocnemius muscle) I/R lesion was induced in rats and different reperfusion times (1 h, 24 h, 72 h, 7-day, and 14-day subgroups) were assessed. Furthermore, levels of oxidative markers such as enzymatic scavengers (catalase (CAT) and superoxide dismutase (SOD)) and metabolites (nitrates and 8-oxo-deoxyguanosine) were determined. The degree of tissue injury (total lesioned fibers and inflammatory cell count) was also evaluated. We observed an increase in CAT and SOD expression levels under telmisartan treatment, with a decrease in injury and oxidative biomarker levels in the 72 h, 7-day, and 14-day subgroups. Telmisartan reduced oxidative stress and decreased the damage of the I/R lesion." @default.
- W2955897025 created "2019-07-12" @default.
- W2955897025 creator A5011191709 @default.
- W2955897025 creator A5012890595 @default.
- W2955897025 creator A5019937384 @default.
- W2955897025 creator A5028974478 @default.
- W2955897025 creator A5049562647 @default.
- W2955897025 creator A5054231775 @default.
- W2955897025 creator A5059311832 @default.
- W2955897025 creator A5070719994 @default.
- W2955897025 date "2019-07-02" @default.
- W2955897025 modified "2023-09-26" @default.
- W2955897025 title "Effect of Telmisartan in the Oxidative Stress Components Induced by Ischemia Reperfusion in Rats" @default.
- W2955897025 cites W1531133799 @default.
- W2955897025 cites W1569955072 @default.
- W2955897025 cites W1920054367 @default.
- W2955897025 cites W1970240791 @default.
- W2955897025 cites W1971462915 @default.
- W2955897025 cites W1976560256 @default.
- W2955897025 cites W1980053858 @default.
- W2955897025 cites W1985536050 @default.
- W2955897025 cites W1987321293 @default.
- W2955897025 cites W1990744119 @default.
- W2955897025 cites W1991627669 @default.
- W2955897025 cites W1997023449 @default.
- W2955897025 cites W2005661035 @default.
- W2955897025 cites W2012154760 @default.
- W2955897025 cites W2029410726 @default.
- W2955897025 cites W2032438124 @default.
- W2955897025 cites W2033204507 @default.
- W2955897025 cites W2033620247 @default.
- W2955897025 cites W2034383851 @default.
- W2955897025 cites W2035547373 @default.
- W2955897025 cites W2038826532 @default.
- W2955897025 cites W2044412059 @default.
- W2955897025 cites W204998232 @default.
- W2955897025 cites W2050118590 @default.
- W2955897025 cites W2051395985 @default.
- W2955897025 cites W2058062846 @default.
- W2955897025 cites W2059101606 @default.
- W2955897025 cites W2062778001 @default.
- W2955897025 cites W2062991061 @default.
- W2955897025 cites W2063146732 @default.
- W2955897025 cites W2066660718 @default.
- W2955897025 cites W2073066341 @default.
- W2955897025 cites W2084295877 @default.
- W2955897025 cites W2087202910 @default.
- W2955897025 cites W2107886181 @default.
- W2955897025 cites W2115119825 @default.
- W2955897025 cites W2118676803 @default.
- W2955897025 cites W2123243699 @default.
- W2955897025 cites W2125167727 @default.
- W2955897025 cites W2128473487 @default.
- W2955897025 cites W2142211652 @default.
- W2955897025 cites W2142381016 @default.
- W2955897025 cites W2159245100 @default.
- W2955897025 cites W2166531590 @default.
- W2955897025 cites W2168211810 @default.
- W2955897025 cites W2169328873 @default.
- W2955897025 cites W2171165037 @default.
- W2955897025 cites W2292493149 @default.
- W2955897025 cites W2407406014 @default.
- W2955897025 cites W2415890695 @default.
- W2955897025 cites W2419093187 @default.
- W2955897025 cites W2498215202 @default.
- W2955897025 cites W2518333018 @default.
- W2955897025 cites W2560116408 @default.
- W2955897025 cites W2566333039 @default.
- W2955897025 cites W2587769401 @default.
- W2955897025 cites W2760966539 @default.
- W2955897025 cites W2795489308 @default.
- W2955897025 cites W3192068087 @default.
- W2955897025 cites W4211073154 @default.
- W2955897025 cites W4255683973 @default.
- W2955897025 cites W785895034 @default.
- W2955897025 doi "https://doi.org/10.1155/2019/1302985" @default.
- W2955897025 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6636510" @default.
- W2955897025 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31354899" @default.
- W2955897025 hasPublicationYear "2019" @default.
- W2955897025 type Work @default.
- W2955897025 sameAs 2955897025 @default.
- W2955897025 citedByCount "9" @default.
- W2955897025 countsByYear W29558970252019 @default.
- W2955897025 countsByYear W29558970252020 @default.
- W2955897025 countsByYear W29558970252021 @default.
- W2955897025 countsByYear W29558970252022 @default.
- W2955897025 crossrefType "journal-article" @default.
- W2955897025 hasAuthorship W2955897025A5011191709 @default.
- W2955897025 hasAuthorship W2955897025A5012890595 @default.
- W2955897025 hasAuthorship W2955897025A5019937384 @default.
- W2955897025 hasAuthorship W2955897025A5028974478 @default.
- W2955897025 hasAuthorship W2955897025A5049562647 @default.
- W2955897025 hasAuthorship W2955897025A5054231775 @default.
- W2955897025 hasAuthorship W2955897025A5059311832 @default.
- W2955897025 hasAuthorship W2955897025A5070719994 @default.
- W2955897025 hasBestOaLocation W29558970251 @default.
- W2955897025 hasConcept C126322002 @default.
- W2955897025 hasConcept C134018914 @default.