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• W2955900336 endingPage "e0217045" @default.
• W2955900336 startingPage "e0217045" @default.
• W2955900336 abstract "Purpose High calorie intake leads to obesity, a global socio-economic and health problem, reaching epidemic proportion in children and adolescents. Saturated and monounsaturated fatty acids from animal (lard) fat are major components of the western-pattern diet and its regular consumption leads to obesity, a risk factor for cardiovascular disease. However, no clear evidence exists whether consumption of diet rich in saturated (SFAs) and monounsaturated (MUFAs) fatty acids has detrimental effects on cardiac structure and energetics primarily due to excessive calories. We, therefore, sought to determine the impact of high calories versus fat content in diet on cardiac structure and mitochondrial energetics. Methods Six-week-old C57BL/6J mice were fed with high calorie, high lard fat-based diet (60% fat, HFD), high-calorie and low lard fat-based diet (10% fat, LFD), and lower-calorie and fat diet (standard chow, 12% fat, SCD) for 10 weeks. Results The HFD- and LFD-fed mice had higher body weight, ventricular mass and thickness of posterior and septal wall with increased cardiomyocytes diameter compared to the SCD-fed mice. These changes were associated with a reduction in the mitochondrial oxidative phosphorylation (OXPHOS) complexes I and III activity compared to the SCD-fed mice without significant differences between the HFD- and LFD-fed animals. The HFD-fed animals had higher level of malondialdehyde (MDA) than LFD and SCD-fed mice. Conclusions We assume that changes in cardiac morphology and selective reduction of the OXPHOS complexes activity observed in the HFD- and LFD-fed mice might be related to excessive calories with additional effect of fat content on oxidative stress." @default.
• W2955900336 created "2019-07-12" @default.
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• W2955900336 date "2019-07-02" @default.
• W2955900336 modified "2023-10-16" @default.
• W2955900336 title "High calories but not fat content of lard-based diet contribute to impaired mitochondrial oxidative phosphorylation in C57BL/6J mice heart" @default.
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• W2955900336 cites W1989133070 @default.
• W2955900336 cites W1998319035 @default.
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• W2955900336 cites W2144727133 @default.
• W2955900336 cites W2147382256 @default.
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• W2955900336 doi "https://doi.org/10.1371/journal.pone.0217045" @default.
• W2955900336 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6605645" @default.
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• W2955900336 hasPublicationYear "2019" @default.
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