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- W2955986346 endingPage "115033" @default.
- W2955986346 startingPage "115033" @default.
- W2955986346 abstract "Hyaluronic acid (HA), a naturally sourced polysaccharide, has shown remarkable effectiveness on wound healing, but its low mechanical strength and instability limits its frequent application in this field. In order to minimize this shortcoming, hyaluronic acid based wound dressings were blended with functionalized ZIF-8, which not only provides high mechanical strength, but also introduces antibacterial properties and promotes fibroblast migration and proliferation. To analyze physiochemical and biological characteristics of prepared wound dressings, tests including DLS, XRD, FTIR as well as antibacterial and cell adhesion assays were carried out. Results indicated that HA film modification boosted the Young’s modulus from 138 to 176 K Pa, and reduced the water contact angle from 37.4 to 27.7 proving enhancement in hydrophilicity. Ameliorated antibacterial properties and better cell adhesion were also observed. Suitable cell viability was observed in samples with FZIF-8, since released Zn ions maintained within a safe concentration range." @default.
- W2955986346 created "2019-07-12" @default.
- W2955986346 creator A5033482691 @default.
- W2955986346 creator A5059265351 @default.
- W2955986346 creator A5061213307 @default.
- W2955986346 creator A5066169847 @default.
- W2955986346 date "2019-10-01" @default.
- W2955986346 modified "2023-10-09" @default.
- W2955986346 title "Hyaluronic acid/ carboxylated Zeolitic Imidazolate Framework film with improved mechanical and antibacterial properties" @default.
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- W2955986346 doi "https://doi.org/10.1016/j.carbpol.2019.115033" @default.
- W2955986346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31320054" @default.
- W2955986346 hasPublicationYear "2019" @default.
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